Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | EDNRA | P25101 | 1/20 | 0.49 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.49 |
| ▸ | TOP1 | P11387 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10654741 | 0.99 | DPP4 (0.60) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9150328 | 0.93 | DPP4 (0.67) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL10654645 | 0.91 | DPP4 (0.58) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL10656681 | 0.89 | DPP4 (0.56) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL7837172 | 0.88 | DPP4 (0.57) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL7837178 | 0.88 | DPP4 (0.57) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9303242 | 0.88 | DPP4 (0.57) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL10655952 | 0.87 | DPP4 (0.50) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9382133 | 0.87 | DPP4 (0.58) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL10928412 | 0.87 | DPP4 (0.64) | DPP4CHRM2DRD1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4649144-A | Antibacterial 7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1987-03-10 | — | — | US | claimed |
| EP-0132845-A2 | Novel 1,8-Naphthyridine derivatives, and process for preparation thereof | Dainippon Pharmaceutical Co., Ltd. (JP) | 1985-02-13 | — | — | EP | claimed |
| US-7320985-B2 | Method for stabilizing arylcarboxylic acid, stabilizer thereof and aqueous solution containing stabilized arylcarboxylic acid | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2008-01-22 | — | — | US | disclosed |
| EP-1389469-B1 | Method for stabilizing arylcarboxylic acid, stabilizer thereof and aqueous solution containing stabilized arylcarboxylic acid | SENJU PHARMA CO (JP) | 2005-10-26 | — | — | EP | disclosed |
| US-20050075350-A1 | Method for stabilizing arylcarboxylic acid, stabilizer thereof and aqueous solution containing stabilized arylcarboxylic acid | SAWA SHIROU (JP) | 2005-04-07 | — | — | US | disclosed |
| EP-1044688-B1 | METHOD FOR SOLUBILIZING PYRIDONECARBOXYLIC ACIDS AND AQUEOUS SOLUTIONS CONTAINING PYRIDONECARBOXYLIC ACIDS | SENJU PHARMA CO (JP) | 2004-12-01 | — | — | EP | disclosed |
| EP-1389469-A1 | Method for stabilizing arylcarboxylic acid, stabilizer thereof and aqueous solution containing stabilized arylcarboxylic acid | Senju Pharmaceutical Co., Ltd. (JP) | 2004-02-18 | — | — | EP | disclosed |
| EP-0856310-B1 | Method for stabilizing arylcarboxylic acid, stabilizer thereof and aqueous solution containing stabilized arylcarboxylic acid | SENJU PHARMA CO (JP) | 2003-11-12 | — | — | EP | disclosed |
| US-20010056098-A1 | Method for stabilizing arylcarboxylic acid, stabilizer thereof and aqueous solution containing stabilized arylcarboxylic acid | SAWA SHIROU (JP) | 2001-12-27 | — | — | US | disclosed |
| US-6306856-B1 | DISSOLVING PYRIDONECARBOXYLIC ACID OR SALT, MIXING WITH GLYCYRRHIZIC ACID WITH ACID | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2001-10-23 | — | — | US | disclosed |
| US-6274592-B1 | ADDING FUSED NITROGEN-HETEROCYCLIC BASE SUCH AS PURINE DERIVATIVE | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2001-08-14 | — | — | US | disclosed |
| EP-1044688-A1 | METHOD FOR SOLUBILIZING PYRIDONECARBOXYLIC ACID, SOLUBILIZER THEREFOR, AQUEOUS SOLUTION PREPARATIONS CONTAINING PYRIDONECARBOXYLIC ACID AND PROCESS FOR PRODUCING THE SAME | Senju Pharmaceutical Co., Ltd. (JP) | 2000-10-18 | — | — | EP | disclosed |
| US-5942508-A | Method for solubilizing pyridonecarboxylic acid solubilizer thereof and aqueous solution containing solubilized pyridonecarboxylic acid | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1999-08-24 | — | — | US | disclosed |
| US-5858408-A | Sustained-release oral ointment | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0856310-A2 | Method for stabilizing acriylcarboxylic acid, stabilizer thereof and aqueous solution containing stabilized acrylcarboxylic acid | Senju Pharmaceutical Co., Ltd. (JP) | 1998-08-05 | — | — | EP | disclosed |
| EP-0856316-A1 | Method for solubilizing pyridonecarboxylic acid, solubilizer thereof and aqueous solution containing solubilized pyridonecarboxylic acid | Senju Pharmaceutical Co., Ltd. (JP) | 1998-08-05 | — | — | EP | disclosed |
| EP-0788801-A1 | SUSTAINED-RELEASE ORAL OINTMENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |
| EP-0132845-B1 | NOVEL 1,8-NAPHTHYRIDINE DERIVATIVES, AND PROCESS FOR PREPARATION THEREOF | Dainippon Pharmaceutical Co., Ltd. (JP) | 1988-04-13 | — | — | EP | disclosed |
| US-4649144-A | Antibacterial 7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0132845-A2 | Novel 1,8-Naphthyridine derivatives, and process for preparation thereof | Dainippon Pharmaceutical Co., Ltd. (JP) | 1985-02-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075350-A1 | Method for stabilizing arylcarboxylic acid, stabilizer thereof and aqueous solution containing stabilized arylcarboxylic acid | AADAC, AASDHPPT, ALDH7A1 | DPP4 667/4885CHRM2 4821/4885DRD1 1669/4885 |
| US-20010056098-A1 | Method for stabilizing arylcarboxylic acid, stabilizer thereof and aqueous solution containing stabilized arylcarboxylic acid | AADAC, AASDHPPT, ALDH7A1 | DPP4 667/4885CHRM2 4821/4885DRD1 1669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.