Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.62 |
| ▸ | HTR2A | P28223 | 13/20 | 0.62 |
| ▸ | HTR1A | P08908 | 11/20 | 0.62 |
| ▸ | HTR2C | P28335 | 3/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.57 |
| ▸ | HRH1 | P35367 | 3/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4574194 | 0.99 | DRD2 (0.64) | DRD2HTR2AHTR1AHTR2CADRA1A | |
| Methane SCHEMBL4610126 | 0.98 | DRD2 (0.62) | DRD2HTR2AHTR1AHTR2CADRA1A | |
| SCHEMBL4574609 | 0.86 | DRD2 (0.64) | DRD2HTR2AHTR1AHTR2CADRA1A | |
| SCHEMBL29433199 | 0.84 | DRD2 (0.75) | DRD2HTR2AHTR1AHTR2CADRA1A | |
| SCHEMBL4575169 | 0.83 | DRD2 (0.62) | DRD2HTR2AHTR1AHTR2CADRA1A | |
| SCHEMBL4574666 | 0.82 | DRD2 (0.64) | DRD2HTR2AHTR1AHTR2CADRA1A | |
| SCHEMBL4575088 | 0.82 | DRD2 (0.64) | DRD2HTR2AHTR1AHTR2CADRA1A | |
| SCHEMBL4574648 | 0.81 | DRD2 (0.65) | DRD2HTR2AHTR1AHTR2CADRA1A | |
| SCHEMBL4574368 | 0.80 | DRD2 (0.77) | DRD2HTR2AHTR1AHTR2CADRA1A | |
| SCHEMBL4574933 | 0.80 | DRD2 (0.64) | DRD2HTR2AHTR1AHTR2CADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008047883-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENES FOR TREATMENT OF MENTAL DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-04-24 | — | — | WO | claimed |