Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 6/20 | 0.38 |
| ▸ | SLC8A1 | P32418 | 8/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4574531 | 0.91 | SLC8A1 (0.40) | RORCSLC8A1 | |
| SCHEMBL4964550 | 0.88 | HTT (0.38) | SLC8A1 | |
| SCHEMBL4964547 | 0.88 | HTT (0.38) | SLC8A1 | |
| SCHEMBL4962494 | 0.88 | KMT2A (0.37) | SLC8A1 | |
| SCHEMBL4962487 | 0.88 | KMT2A (0.37) | SLC8A1 | |
| SCHEMBL4574373 | 0.88 | SLC8A1 (0.35) | RORCSLC8A1PDK2 | |
| SCHEMBL4590624 | 0.87 | SLC8A1 (0.34) | SLC8A1PDK2 | |
| SCHEMBL4590893 | 0.86 | SLC8A1 (0.33) | SLC8A1 | |
| SCHEMBL4756646 | 0.84 | SLC8A1 (0.33) | SLC8A1 | |
| SCHEMBL4590435 | 0.84 | SLC8A1 (0.34) | SLC8A1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008095912-A2 | ENANTIOPURE PHARMACOLOGICALLY ACTIVE TRICYCLIC BENZIMIDAZOLES | NYCOMED GMBH (DE) | 2008-08-14 | — | — | WO | disclosed |