Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC8A1 | P32418 | 13/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CD38 | P28907 | 2/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4965120 | 0.89 | BRD4 (0.35) | SLC8A1 | |
| SCHEMBL2689406 | 0.89 | SLC8A1 (0.32) | SLC8A1 | |
| SCHEMBL4666543 | 0.88 | RAB9A (0.35) | SLC8A1CYP11B1CYP11B2PARP1 | |
| SCHEMBL4964547 | 0.87 | HTT (0.38) | SLC8A1 | |
| SCHEMBL4964116 | 0.87 | RAB9A (0.36) | SLC8A1 | |
| SCHEMBL4962494 | 0.87 | KMT2A (0.37) | SLC8A1 | |
| SCHEMBL4574962 | 0.87 | SLC8A1 (0.33) | SLC8A1 | |
| SCHEMBL4574970 | 0.87 | SLC8A1 (0.33) | SLC8A1 | |
| SCHEMBL4574967 | 0.87 | SLC8A1 (0.33) | SLC8A1 | |
| SCHEMBL4574531 | 0.86 | SLC8A1 (0.40) | SLC8A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008151927-A2 | 6-N-SUBSTITUTED BENZ IMIDAZOLE DERIVATIVES AS ACID PUMP ANTAGONISTS | NYCOMED GMBH (DE) | 2008-12-18 | — | — | WO | disclosed |