Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | RBP1 | P09455 | 3/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8223152 | 0.99 | KMT2A (0.60) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL4574665 | 0.96 | KMT2A (0.55) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL4574616 | 0.94 | KMT2A (0.50) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL8226396 | 0.93 | KMT2A (0.51) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL8220554 | 0.91 | CCR3 (0.52) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL8224526 | 0.87 | CCR3 (0.53) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL4575246 | 0.87 | HTT (0.57) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL8221253 | 0.87 | KMT2A (0.47) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL4575547 | 0.80 | KMT2A (0.72) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL8220788 | 0.76 | KMT2A (0.64) | KMT2AMEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008050200-A1 | OXADIAZOLE COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-05-02 | — | — | WO | claimed |
| WO-2008050200-A1 | OXADIAZOLE COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-05-02 | — | — | WO | disclosed |