Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | HTR1A | P08908 | 6/20 | 0.49 |
| ▸ | HTR7 | P34969 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8224526 | 0.91 | CCR3 (0.53) | HTTHTR1AHTR7KMT2AALDH1A1 | |
| SCHEMBL4574665 | 0.91 | KMT2A (0.55) | HTTHTR1AHTR7KMT2AALDH1A1 | |
| SCHEMBL8226396 | 0.90 | KMT2A (0.51) | HTTHTR1AHTR7KMT2AALDH1A1 | |
| SCHEMBL4574616 | 0.89 | KMT2A (0.50) | HTTHTR1AHTR7KMT2AALDH1A1 | |
| SCHEMBL8220554 | 0.88 | CCR3 (0.52) | HTTHTR1AHTR7KMT2AALDH1A1 | |
| SCHEMBL8223152 | 0.88 | KMT2A (0.60) | HTTHTR1AHTR7KMT2AALDH1A1 | |
| SCHEMBL4575185 | 0.87 | KMT2A (0.59) | HTTHTR1AHTR7KMT2AALDH1A1 | |
| SCHEMBL8221253 | 0.85 | KMT2A (0.47) | HTTHTR1AHTR7KMT2AALDH1A1 | |
| SCHEMBL4574581 | 0.79 | MEN1 (0.53) | HTTKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL8223148 | 0.77 | PKM (0.47) | HTTKMT2AALDH1A1MEN1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008050200-A1 | OXADIAZOLE COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-05-02 | — | — | WO | claimed |
| WO-2008050200-A1 | OXADIAZOLE COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-05-02 | — | — | WO | disclosed |