Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of 2-Chloropyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Chloropyridine SCHEMBL30961660 | 1.00 | — | — | |
| 2-Chloropyridine SCHEMBL9850322 | 0.97 | — | — | |
| 2-Chloropyridine SCHEMBL10690176 | 0.97 | TDP1 (1.00) | — | |
| 2-Chloropyridine SCHEMBL11389784 | 0.97 | — | — | |
| 2-Chloropyridine SCHEMBL29402311 | 0.97 | — | — | |
| 2-Chloropyridine SCHEMBL28283275 | 0.97 | TDP1 (1.00) | — | |
| 2-Chloropyridine SCHEMBL16637 | 0.97 | — | — | |
| 2-Chloropyridine SCHEMBL1935752 | 0.94 | — | — | |
| 2-Chloropyridine SCHEMBL11437985 | 0.94 | — | — | |
| 2-Chloropyridine SCHEMBL21640063 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108601353-B | Bactericidal composition | 高文作物保护公司 | 2024-04-05 | — | — | CN | disclosed |
| US-11903387-B2 | Fungicidal composition | GOWAN COMPANY, L.L.C. (US) | 2024-02-20 | — | — | US | disclosed |
| CN-114702411-A | Method for producing 1, 2-benzenedimethanol compound | 高文作物保护公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-108602765-B | Method for producing 1, 2-benzenedimethanol compound | 高文有限公司 | 2022-05-03 | — | — | CN | disclosed |
| US-11274076-B2 | Process for preparing 1, 2-benzenedimethanol compound | GOWAN COMPANY, L.L.C. (US) | 2022-03-15 | — | — | US | disclosed |
| US-11141489-B2 | Conjugates comprising an GLP-1/Glucagon dual agonist, a linker and hyaluronic acid | SANOFI (FR) | 2021-10-12 | — | — | US | disclosed |
| US-20210045386-A1 | FUNGICIDAL COMPOSITION | BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT | 2021-02-18 | — | — | US | disclosed |
| US-20200399263-A1 | PROCESS FOR PREPARING 1, 2-BENZENEDIMETHANOL COMPOUND | BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT | 2020-12-24 | — | — | US | disclosed |
| US-10792367-B2 | Conjugates comprising an GLP-1/glucagon dual agonist, a linker and hyaluronic acid | SANOFI (FR) | 2020-10-06 | — | — | US | disclosed |
| CN-106414414-B | Process for producing trione compound | 组合化学工业株式会社 | 2020-07-14 | — | — | CN | disclosed |
| US-5935955-A | SUBSTITUTED 3,6-DIBENZYLIDENE-2,5-PIPERAZINEDIONES, MODULATORS OF MULTIDRUG RESISTANCE | XENOVA LIMITED (GB) | 1999-08-10 | — | — | US | disclosed |
| EP-0799210-A1 | PIPERAZINE-2,5-DIONE DERIVATIVES AS MODULATORS OF MULTIDRUG RESISTANCE | XENOVA LIMITED (GB) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996020180-A1 | PIPERAZINE-2,5-DIONE DERIVATIVES AS MODULATORS OF MULTIDRUG RESISTANCE | XENOVA LIMITED (GB) | 1996-07-04 | — | — | WO | disclosed |
| US-5446158-A | Process for synthesis of FK-506 and tricarbonyl intermediates | MERCK & CO., INC. (US) | 1995-08-29 | — | — | US | disclosed |
| EP-0606044-A1 | Lactones compounds useful as pharmaceuticals | SANDOZ LTD. (CH) | 1994-07-13 | — | — | EP | disclosed |
| CN-1016692-B | METHOD FOR PREPARATION OF TRYCYCLIC PYRIDAZOPYRIDONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1992-05-20 | — | — | CN | disclosed |
| EP-0378318-A1 | Process for synthesis of FK-506 and tricarbonyl intermediates | MERCK & CO. INC. (US) | 1990-07-18 | — | — | EP | disclosed |
| US-4814345-A | ANTIARRHYTHMIA AGENTS | KALI-CHEMIE PHARMA GMBH (DE) | 1989-03-21 | — | — | US | disclosed |
| CN-86108467-A | Three ring pyridazine and Pyridione derivatives | — | 1987-07-08 | — | — | CN | disclosed |
| EP-0050007-B1 | A HEAT-RESISTANT ADENYLATE KINASE, A STABLE IMMOBILIZED ADENYLATE KINASE COMPOSITE MATERIAL, AND PROCESSES FOR THEIR PRODUCTION | UNITIKA LTD. (JP) | 1986-02-05 | — | — | EP | disclosed |