Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of 2-Chloropyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Chloropyridine SCHEMBL30961660 | 0.97 | — | — | |
| 2-Chloropyridine SCHEMBL8545796 | 0.97 | — | — | |
| 2-Chloropyridine SCHEMBL457535 | 0.97 | — | — | |
| 2-Chloropyridine SCHEMBL11389784 | 0.94 | — | — | |
| 2-Chloropyridine SCHEMBL28283275 | 0.94 | TDP1 (1.00) | — | |
| 2-Chloropyridine SCHEMBL10690176 | 0.94 | TDP1 (1.00) | — | |
| 2-Chloropyridine SCHEMBL29402311 | 0.94 | — | — | |
| 2-Chloropyridine SCHEMBL16637 | 0.94 | — | — | |
| 2-Chloropyridine SCHEMBL1935752 | 0.92 | — | — | |
| 2-Chloropyridine SCHEMBL11437985 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433112-A1 | Modified gangliosides and the functional derivatives thereof | FIDIA S.p.A. (IT) | 1991-06-19 | — | — | EP | disclosed |
| EP-0383319-A2 | Imidazopyridines, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-08-22 | — | — | EP | disclosed |
| EP-0373039-A2 | New lysoganglioside derivatives | FIDIA S.p.A. (IT) | 1990-06-13 | — | — | EP | disclosed |