Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19464195 | 1.00 | LMNA (0.48) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL7875788 | 0.91 | LMNA (0.52) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL1705822 | 0.91 | LMNA (0.52) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL1705524 | 0.91 | LMNA (0.52) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL7869209 | 0.91 | LMNA (0.52) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL7863756 | 0.91 | LMNA (0.52) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL18342526 | 0.89 | LMNA (0.50) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL18342558 | 0.89 | LMNA (0.50) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL7870895 | 0.87 | LMNA (0.59) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL10893740 | 0.87 | LMNA (0.59) | LMNAALDH1A1MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614055-A2 | PROCESS FOR PREPARATION OF SUBSTANTIALLY PURE FOSAMPRENAVIR CALCIUM AND ITS INTERMEDIATES | Lupin Limited (IN) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012032389-A2 | PROCESS FOR PREPARATION OF SUBSTANTIALLY PURE FOSAMPRENAVIR CALCIUM AND ITS INTERMEDIATES | LUPIN LIMITED (IN) | 2012-03-15 | — | — | WO | disclosed |