Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CCNC | P24863 | 2/20 | 0.42 |
| ▸ | CDK8 | P49336 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457578 | 1.00 | TTR (0.49) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL29403887 | 0.85 | TTR (0.47) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL22186887 | 0.85 | TTR (0.47) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL17054008 | 0.85 | TTR (0.47) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL4096954 | 0.85 | TTR (0.47) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL4096951 | 0.85 | TTR (0.47) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL29550384 | 0.81 | CA12 (0.51) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL2302128 | 0.81 | CA12 (0.51) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL2302901 | 0.81 | CA12 (0.51) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL13199834 | 0.81 | NPC1 (0.37) | CYP3A4NPC1RAB9AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |