Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CCNC | P24863 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29550384 | 1.00 | CA12 (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2302901 | 1.00 | CA12 (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL22881952 | 0.88 | APP (0.50) | KEAP1NFE2L2NPC1RAB9AHSP90AA1 | |
| SCHEMBL3668367 | 0.85 | LMNA (0.48) | KEAP1NFE2L2NPC1RAB9AMEN1 | |
| SCHEMBL6798384 | 0.85 | ATM (0.53) | KEAP1NFE2L2HSP90AA1ATM | |
| SCHEMBL6798388 | 0.85 | ATM (0.53) | KEAP1NFE2L2HSP90AA1ATM | |
| SCHEMBL28730465 | 0.83 | HSP90AA1 (0.46) | KEAP1NFE2L2NPC1RAB9AHSP90AA1 | |
| SCHEMBL27224520 | 0.83 | APP (0.54) | ATMLMNACYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL643378 | 0.81 | HSP90AA1 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL643379 | 0.81 | HSP90AA1 (0.53) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114196309-B | Weather-resistant self-repairing coating and preparation method thereof | 广东美涂士建材股份有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-114196309-A | Weather-resistant self-repairing coating and preparation method thereof | 广东美涂士建材股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-111138350-B | Asymmetric synthesis method of dexchlorpheniramine and dexbrompheniramine | 中国药科大学 | 2021-08-10 | — | — | CN | claimed |
| CN-111138350-A | Asymmetric synthesis method of dexchlorpheniramine and dexbrompheniramine | 中国药科大学 | 2020-05-12 | — | — | CN | claimed |
| CN-119604488-A | Protein tyrosine kinase inhibitor and medical application thereof | 苏州必扬医药科技有限公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-114196309-B | Weather-resistant self-repairing coating and preparation method thereof | 广东美涂士建材股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114196309-A | Weather-resistant self-repairing coating and preparation method thereof | 广东美涂士建材股份有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-111138350-B | Asymmetric synthesis method of dexchlorpheniramine and dexbrompheniramine | 中国药科大学 | 2021-08-10 | — | — | CN | disclosed |
| CN-111138350-B | Asymmetric synthesis method of dexchlorpheniramine and dexbrompheniramine | 中国药科大学 | 2021-08-10 | — | — | CN | disclosed |
| CN-111138350-A | Asymmetric synthesis method of dexchlorpheniramine and dexbrompheniramine | 中国药科大学 | 2020-05-12 | — | — | CN | disclosed |
| CN-111138350-A | Asymmetric synthesis method of dexchlorpheniramine and dexbrompheniramine | 中国药科大学 | 2020-05-12 | — | — | CN | disclosed |
| EP-3004118-B1 | USE OF CONDENSED BENZO[B]THIAZINE DERIVATIVES AS CYTOPROTECTANTS | ARANDA PHARMA LTD (FI) | 2018-12-19 | — | — | EP | disclosed |
| EP-1124822-A1 | THROMBIN INHIBITORS | Merck & Co., Inc. (US) | 2001-08-22 | — | — | EP | disclosed |
| EP-0694546-B1 | Substituted dibenzoxazepine compounds, pharmaceutical compositions and use | SEARLE & CO (US) | 2001-06-06 | — | — | EP | disclosed |
| WO-2000026211-A1 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2000-05-11 | — | — | WO | disclosed |
| EP-0839798-A2 | Intermediates for preparating non-peptide retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1998-05-06 | — | — | EP | disclosed |
| US-5670675-A | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1997-09-23 | — | — | US | disclosed |
| US-5545750-A | TREATING HUMAN IMMUNODEFICIENCY VIRUS | ABBOTT LABORATORIES (US) | 1996-08-13 | — | — | US | disclosed |
| US-5142056-A | Human immunodeficiency virus protease inhibitor | ABBOTT LABORATORIES (US) | 1992-08-25 | — | — | US | disclosed |
| EP-0402646-A1 | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1990-12-19 | — | — | EP | disclosed |