Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | BACE1 | P56817 | 4/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.46 |
| ▸ | ABL1 | P00519 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.45 |
| ▸ | BCR | P11274 | 2/20 | 0.45 |
| ▸ | PDE4A | P27815 | 3/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7647539 | 0.88 | CA1 (0.59) | CA1CA2BACE1ABL1ABCB1 | |
| SCHEMBL5989278 | 0.84 | BACE1 (0.73) | BACE1PDE4BABL1ABCB1BCR | |
| SCHEMBL240515 | 0.84 | CA2 (0.80) | CA1CA2MEN1KMT2AALDH1A1 | |
| SCHEMBL29602570 | 0.84 | CA2 (0.80) | CA1CA2MEN1KMT2AALDH1A1 | |
| Phenol SCHEMBL9404586 | 0.81 | CA2 (0.75) | CA1CA2BACE1PDE4BABL1 | |
| SCHEMBL510694 | 0.81 | CA2 (0.59) | CA1CA2BACE1PDE4BMEN1 | |
| SCHEMBL21753677 | 0.80 | CA2 (0.57) | CA1CA2BACE1PDE4BMEN1 | |
| SCHEMBL29933298 | 0.79 | CA2 (0.61) | CA1CA2BACE1ABL1ABCB1 | |
| SCHEMBL7645330 | 0.79 | CA2 (0.61) | CA1CA2BACE1ABL1ABCB1 | |
| SCHEMBL39130 | 0.78 | CA2 (1.00) | CA1CA2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371879-B2 | Bivalent monomeric phenoxy tin compounds | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-05-13 | — | — | US | claimed |
| US-20070244325-A1 | Polymerization processes using bivalent monomeric phenoxy tin catalysts | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-10-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244325-A1 | Polymerization processes using bivalent monomeric phenoxy tin catalysts | PCNA, BMI1, TET2 | CA1 4399/4885CA2 3703/4885BACE1 4459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.