SCHEMBL4576136

SCHEMBL4576136

O=C(O)[C@H](CS)N(Cc1ccccc1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
CPA3 P15088 1/20 0.49
FOLH1 Q04609 1/20 0.49
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
POLB P06746 1/20 0.46
HSD17B10 Q99714 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CA12 O43570 1/20 0.44
CA9 Q16790 1/20 0.44
MME P08473 3/20 0.42
CTRB1 P17538 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9657305 0.88 MEN1 (0.49) MEN1KMT2ACPA3FOLH1ALDH1A1
SCHEMBL28716250 0.88 MEN1 (0.49) MEN1KMT2ACPA3FOLH1ALDH1A1
SCHEMBL2327943 0.87 KMT2A (0.46) MEN1KMT2ACPA3FOLH1ALDH1A1
SCHEMBL2330584 0.87 MEN1 (0.47) MEN1KMT2ACPA3FOLH1ALDH1A1
SCHEMBL28288519 0.85 MEN1 (0.46) MEN1KMT2ACPA3FOLH1ALDH1A1
SCHEMBL27004114 0.84 FOLH1 (0.50) MEN1KMT2ACPA3FOLH1CA12
SCHEMBL27004369 0.84 FOLH1 (0.50) MEN1KMT2ACPA3FOLH1CA12
SCHEMBL3225070 0.84 KMT2A (0.50) MEN1KMT2AALDH1A1LMNAPOLB
SCHEMBL7275088 0.83 ALDH1A1 (0.52) MEN1KMT2ACPA3FOLH1ALDH1A1
SCHEMBL11582506 0.82 FOLH1 (0.49) MEN1KMT2ACPA3FOLH1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7335717-B2 Methods, compositions, and biomimetic catalysts for the synthesis of silica, polysilsequioxanes, polysiloxanes, non-silicon metalloid-oxygen networks, polymetallo-oxanes, and their organic or hydrido conjugates and derivatives THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-02-26 US disclosed
US-20050090634-A1 Methods, compositions, and biomimetic catalysts for the synthesis of silica, polysilsequioxanes, polysiloxanes, non-silicon metalloid-oxygen networks, polymetallo-oxanes, and their organic or hydrido conjugates and derivatives NATIONAL SCIENCE FOUNDATION 2005-04-28 US disclosed
US-6670438-B1 Silicatein; polypeptides THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2003-12-30 US disclosed
EP-1153063-A4 METHODS, COMPOSITIONS, AND BIOMIMETIC CATALYSTS FOR IN VITRO SYNTHESIS OF SILICA, POLYSILSEQUIOXANE, POLYSILOXANE, AND POLYMETALLO-OXANES UNIV CALIFORNIA (US) 2003-05-28 EP disclosed
EP-1153063-A1 METHODS, COMPOSITIONS, AND BIOMIMETIC CATALYSTS FOR IN VITRO SYNTHESIS OF SILICA, POLYSILSEQUIOXANE, POLYSILOXANE, AND POLYMETALLO-OXANES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-11-14 EP disclosed
WO-2000035993-A1 METHODS, COMPOSITIONS, AND BIOMIMETIC CATALYSTS FOR IN VITRO SYNTHESIS OF SILICA, POLYSILSEQUIOXANE, POLYSILOXANE, AND POLYMETALLO-OXANES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-06-22 WO disclosed