⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| E927A SCHEMBL4576267 | 1.00 | — | — | |
| E927A SCHEMBL36851 | 0.95 | — | — | |
| E927A SCHEMBL26646 | 0.95 | — | — | |
| E927A SCHEMBL5599354 | 0.95 | ALDH1A1 (1.00) | — | |
| E927A SCHEMBL9921280 | 0.95 | — | — | |
| E927A SCHEMBL11842709 | 0.95 | ALDH1A1 (1.00) | — | |
| E927A SCHEMBL5072650 | 0.91 | ALDH1A1 (0.91) | — | |
| E927A SCHEMBL28500344 | 0.91 | — | — | |
| E927A SCHEMBL28486798 | 0.91 | — | — | |
| E927A SCHEMBL28171740 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109666121-B | Hybrid dynamic cross-linked polymer and application thereof | 厦门逍扬运动科技有限公司 | 2023-09-22 | — | — | CN | disclosed |
| US-7456298-B2 | Synthesis of acetonides from aryl silanes | GENENCOR INTERNATIONAL, INC. (US) | 2008-11-25 | — | — | US | disclosed |
| US-7381830-B2 | Synthesis of cis-diols from aryl silanes | GENENCOR INTERNATIONAL, INC. (US) | 2008-06-03 | — | — | US | disclosed |
| EP-1534783-A4 | SYNTHESIS OF CIS-DIOLS FROM ARYL SILANES | DOW CORNING (US) | 2008-01-09 | — | — | EP | disclosed |
| US-20070213541-A1 | Synthesis of acetonides from aryl silanes | DOW CORNING CORPORATION | 2007-09-13 | — | — | US | disclosed |
| US-20070213550-A1 | Synthesis of cis-diols from aryl silanes | DOW CORNING CORPORATION | 2007-09-13 | — | — | US | disclosed |
| US-7179932-B2 | Synthesis of cis-diols from aryl silanes | GENENCOR INTERNATIONAL, INC. (US) | 2007-02-20 | — | — | US | disclosed |
| EP-1534783-A2 | SYNTHESIS OF CIS-DIOLS FROM ARYL SILANES | Dow Corning Corporation (US) | 2005-06-01 | — | — | EP | disclosed |
| US-20040033574-A1 | Synthesis of cis-diols from aryl silanes | DOW CORNING CORPORATION | 2004-02-19 | — | — | US | disclosed |
| WO-2003102217-A2 | SYNTHESIS OF CIS-DIOLS FROM ARYL SILANES | DOW CORNING CORPORATION (US) | 2003-12-11 | — | — | WO | disclosed |