SCHEMBL4576305

SCHEMBL4576305

CC1=C([Ti](C)(C)([SiH3])c2cccc3c2Cc2ccccc2-3)CC=C1.[H-].[H-]

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.38
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
PGR P06401 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL394937 0.82 PNMT (0.38) PNMTNPC1RAB9APGR
Hydrochloric Acid SCHEMBL5909845 0.71 PNMT (0.36) PNMTNPC1RAB9A
Hydrochloric Acid SCHEMBL4465758 0.70 PNMT (0.38) PNMTNPC1RAB9A
SCHEMBL7754800 0.69 PNMT (0.50) PNMTNPC1RAB9APGR
SCHEMBL7209740 0.68 PNMT (0.36) PNMTNPC1RAB9A
Hydrochloric Acid SCHEMBL28332079 0.68 PNMT (0.49) PNMTNPC1RAB9APGR
Hydrochloric Acid SCHEMBL7780981 0.68 PNMT (0.49) PNMTNPC1RAB9APGR
Hydrochloric Acid SCHEMBL396688 0.68 PNMT (0.49) PNMTNPC1RAB9APGR
Hydrochloric Acid SCHEMBL394715 0.67 PNMT (0.35) PNMTNPC1RAB9A
SCHEMBL7751995 0.66 PNMT (0.47) PNMTNPC1RAB9APGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1448568-A4 DICOPS CONTAINING ACETYLENIC SUBSTITUENTS EXXONMOBIL CHEM PATENTS INC (US) 2008-02-13 EP disclosed
EP-1448568-A2 DICOPS CONTAINING ACETYLENIC SUBSTITUENTS ExxonMobil Chemical Patents Inc. (US) 2004-08-25 EP disclosed
WO-2003040070-A2 DICOPS CONTAINING ACETYLENIC SUBSTITUENTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2003-05-15 WO disclosed