Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.65 |
| ▸ | NQO2 | P16083 | 2/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.47 |
| ▸ | TUBB | P07437 | 3/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4576311 | 1.00 | NFE2L2 (0.65) | NFE2L2NQO2PTGS1TUBB1TUBB4A | |
| SCHEMBL30842569 | 0.92 | NFE2L2 (0.59) | NFE2L2NQO2PTGS1TUBB1TUBB4A | |
| SCHEMBL4575923 | 0.86 | NFE2L2 (0.46) | NFE2L2NQO2PTGS1TUBB1TUBB4A | |
| SCHEMBL4575925 | 0.86 | NFE2L2 (0.46) | NFE2L2NQO2PTGS1TUBB1TUBB4A | |
| SCHEMBL4576391 | 0.85 | TUBB1 (0.67) | NFE2L2NQO2PTGS1TUBB1TUBB4A | |
| SCHEMBL4576395 | 0.85 | TUBB1 (0.67) | NFE2L2NQO2PTGS1TUBB1TUBB4A | |
| SCHEMBL4576577 | 0.83 | NFE2L2 (0.53) | NFE2L2PTGS1TUBB1TUBB4ATUBB | |
| SCHEMBL4576575 | 0.83 | NFE2L2 (0.53) | NFE2L2PTGS1TUBB1TUBB4ATUBB | |
| SCHEMBL919000 | 0.83 | TUBB1 (0.66) | NFE2L2NQO2TUBB1TUBB4ATUBB | |
| SCHEMBL918999 | 0.83 | TUBB1 (0.66) | NFE2L2NQO2TUBB1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1688535-B | Novel bioactive diphenyl ethene compounds and their therapeutic applications | BEIJING WENFENG TIANJI MEDICINE TECHNOLOGY CO LTD | 2011-11-09 | — | — | CN | claimed |
| US-7321050-B2 | Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues | WELICHEM BIOTECH INC. (CA) | 2008-01-22 | — | — | US | claimed |
| CN-1688535-B | Novel bioactive diphenyl ethene compounds and their therapeutic applications | BEIJING WENFENG TIANJI MEDICINE TECHNOLOGY CO LTD | 2011-11-09 | — | — | CN | disclosed |
| US-20080255245-A1 | Anti-Inflammatory and Psoriasis Treatment and Protein Kinase Inhibition by Hydroxystilbenes and Novel Stilbene Derivatives and Analogues | WELICHEM BIOTECH INC. (CA) | 2008-10-16 | — | — | US | disclosed |
| US-7321050-B2 | Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues | WELICHEM BIOTECH INC. (CA) | 2008-01-22 | — | — | US | disclosed |
| CN-1688535-A | Novel bioactive diphenyl ethene compounds and their therapeutic applications | WELICHEM BIOTECH INC (CA) | 2005-10-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255245-A1 | Anti-Inflammatory and Psoriasis Treatment and Protein Kinase Inhibition by Hydroxystilbenes and Novel Stilbene Derivatives and Analogues | NFKBIA, IKBKB, IKBKE | NFE2L2 344/4885NQO2 2595/4885PTGS1 224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.