SCHEMBL4576369

SCHEMBL4576369

NC(=O)C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 3/20 0.63
SLC6A2 P23975 1/20 0.59
OPRD1 P41143 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4576363 1.00 OPRM1 (0.63) OPRM1SLC6A2OPRD1
SCHEMBL30382471 0.93 OPRM1 (0.67) OPRM1SLC6A2OPRD1
SCHEMBL31410861 0.92 OPRM1 (0.60) OPRM1SLC6A2OPRD1
Lysine SCHEMBL185235 0.91 OPRM1 (0.66) OPRM1SLC6A2OPRD1
SCHEMBL29630405 0.90 SLC6A2 (0.59) OPRM1SLC6A2OPRD1
SCHEMBL31676579 0.90 OPRM1 (0.63) OPRM1SLC6A2OPRD1
SCHEMBL29713420 0.89 SLC6A2 (0.62) OPRM1SLC6A2OPRD1
SCHEMBL30423227 0.89 OPRM1 (0.74) OPRM1SLC6A2OPRD1
SCHEMBL29377141 0.89 OPRM1 (0.61) OPRM1SLC6A2OPRD1
SCHEMBL29571797 0.89 OPRM1 (0.74) OPRM1SLC6A2OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1635872-A4 ANTIBODIES AND FUSION PROTEINS THAT INCLUDE ENGINEERED CONSTANT REGIONS ALEXION PHARMA INC (US) 2008-01-02 EP claimed
EP-1635872-A2 ANTIBODIES AND FUSION PROTEINS THAT INCLUDE ENGINEERED CONSTANT REGIONS ALEXION PHARMACEUTICALS, INC. (US) 2006-03-22 EP claimed
WO-2005007809-A2 ANTIBODIES AND FUSION PROTEINS THAT INCLUDE ENGINEERED CONSTANT REGIONS ALEXION PHARMACEUTICALS, INC. (US) 2005-01-27 WO claimed
CN-115960168-A Pearl peptide with multiple effects and preparation method and application thereof 广东海洋大学 2023-04-14 CN disclosed
EP-1567541-A4 RATIONALLY DESIGNED ANTIBODIES ALEXION PHARMA INC (US) 2006-08-02 EP disclosed
EP-1567541-A2 RATIONALLY DESIGNED ANTIBODIES ALEXION PHARMACEUTICALS, INC. (US) 2005-08-31 EP disclosed
WO-2005060642-A2 RATIONALLY DESIGNED ANTIBODIES ALEXION PHARMACEUTICALS, INC. (US) 2005-07-07 WO disclosed
WO-2004108078-A2 RATIONALLY DESIGNED ANTIBODIES ALEXION PHARMACEUTICALS INC. (US) 2004-12-16 WO disclosed
WO-2004050017-A2 RATIONALLY DESIGNED ANTIBODIES ALEXION PHARMACEUTICALS, INC. (US) 2004-06-17 WO disclosed
EP-1370589-A2 RATIONALLY DESIGNED ANTIBODIES ALEXION PHARMACEUTICALS, INC. (US) 2003-12-17 EP disclosed
WO-2002046238-A2 RATIONALLY DESIGNED ANTIBODIES ALEXION PHARMACEUTICALS, INC. (US) 2002-06-13 WO disclosed