Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | TACR2 | P21452 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27508667 | 0.89 | KCNH2 (0.50) | KCNH2SIGMAR1HSD17B10TSHRCA2 | |
| SCHEMBL547838 | 0.89 | KCNH2 (0.60) | KCNH2SIGMAR1HSD17B10CA2CA1 | |
| SCHEMBL2866651 | 0.87 | HSD17B10 (0.53) | HSD17B10TSHRCA2CA1PLK1 | |
| SCHEMBL8776979 | 0.83 | KCNH2 (0.63) | KCNH2SIGMAR1HSD17B10LMNAALDH1A1 | |
| SCHEMBL28534367 | 0.81 | KCNH2 (0.61) | KCNH2SIGMAR1HSD17B10LMNAALDH1A1 | |
| SCHEMBL28525880 | 0.81 | KCNH2 (0.61) | KCNH2SIGMAR1HSD17B10LMNAALDH1A1 | |
| SCHEMBL7655510 | 0.80 | KCNH2 (0.56) | KCNH2SIGMAR1HSD17B10CA2CA1 | |
| SCHEMBL9711161 | 0.80 | ESR1 (0.63) | KCNH2HSD17B10CA2CA1LMNA | |
| SCHEMBL12752951 | 0.80 | KCNH2 (0.56) | KCNH2SIGMAR1HSD17B10CA2CA1 | |
| SCHEMBL7652240 | 0.79 | HPGD (0.50) | KCNH2SIGMAR1PLK1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806220-B2 | COORDINATION CATALYST FOR POLYOLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-10-19 | — | — | US | claimed |
| EP-1296991-B1 | SILOXY SUBSTITUTED COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2013-05-15 | — | — | EP | disclosed |
| EP-1448568-A4 | DICOPS CONTAINING ACETYLENIC SUBSTITUENTS | EXXONMOBIL CHEM PATENTS INC (US) | 2008-02-13 | — | — | EP | disclosed |
| US-6909008-B2 | Cocatalyst compositions | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2005-06-21 | — | — | US | disclosed |
| EP-1259553-B1 | HIGH ACTIVITY CARBENIUM-ACTIVATED POLYMERIZATION CATALYSTS | EXXONMOBIL CHEM PATENTS INC (US) | 2005-01-12 | — | — | EP | disclosed |
| EP-1129115-B1 | OLEFIN COPOLYMERIZATION PROCESS WITH BRIDGED HAFNOCENES | EXXONMOBIL CHEM PATENTS INC (US) | 2004-12-08 | — | — | EP | disclosed |
| US-6806220-B2 | COORDINATION CATALYST FOR POLYOLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-10-19 | — | — | US | disclosed |
| US-20040199021-A1 | DICOPS CONTAINING ACETYLENIC SUBSTITUENTS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-10-07 | — | — | US | disclosed |
| EP-1448568-A2 | DICOPS CONTAINING ACETYLENIC SUBSTITUENTS | ExxonMobil Chemical Patents Inc. (US) | 2004-08-25 | — | — | EP | disclosed |
| US-20040152591-A1 | Polymerized metallocene catalyst composition | EXXONMOBIL CHEMICAL PATENTS, INC. | 2004-08-05 | — | — | US | disclosed |
| WO-2003040070-A2 | DICOPS CONTAINING ACETYLENIC SUBSTITUENTS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2003-05-15 | — | — | WO | disclosed |
| US-6562919-B2 | Bridged hafnocene catalyst complexes activated with cocatalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2003-05-13 | — | — | US | disclosed |
| EP-1259553-A1 | HIGH ACTIVITY CARBENIUM-ACTIVATED POLYMERIZATION CATALYSTS | EXXON CHEMICAL PATENTS INC. (US) | 2002-11-27 | — | — | EP | disclosed |
| US-6486088-B1 | High activity carbenium-activated polymerization catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-11-26 | — | — | US | disclosed |
| US-20020165086-A1 | High activity carbenium-activated polymerization catalysts | CROWTHER DONNA JEAN (US) | 2002-11-07 | — | — | US | disclosed |
| US-20020086958-A1 | High activity carbenium-activated polymerization catalysts | UNIVATION TECHNOLOGIES, LLC | 2002-07-04 | — | — | US | disclosed |
| US-6300433-B1 | Olefin copolymerization process with bridged hafnocenes | EXXONMOBIL CHEMICAL PATENTS INC. | 2001-10-09 | — | — | US | disclosed |
| EP-1129115-A1 | OLEFIN COPOLYMERIZATION PROCESS WITH BRIDGED HAFNOCENES | ExxonMobil Chemical Patents Inc. (US) | 2001-09-05 | — | — | EP | disclosed |
| WO-2001029096-A1 | HIGH ACTIVITY CARBENIUM-ACTIVATED POLYMERIZATION CATALYSTS | EXXON CHEMICAL PATENTS INC. (US) | 2001-04-26 | — | — | WO | disclosed |
| WO-2000024792-A1 | OLEFIN COPOLYMERIZATION PROCESS WITH BRIDGED HAFNOCENES | EXXON CHEMICAL PATENTS INC. (US) | 2000-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040199021-A1 | DICOPS CONTAINING ACETYLENIC SUBSTITUENTS | AADAC, NAA15, ALG8 | KCNH2 4221/4885SIGMAR1 2421/4885HSD17B10 2177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.