Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547838 | 0.89 | KCNH2 (0.60) | HPGDNPC1RAB9AKCNH2ALDH1A1 | |
| SCHEMBL48879 | 0.87 | HPGD (0.58) | HPGDNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL14127779 | 0.87 | HPGD (0.58) | HPGDNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL4823761 | 0.85 | HPGD (0.39) | HPGDNPC1RAB9AKCNH2ALDH1A1 | |
| SCHEMBL6927738 | 0.83 | CNR2 (0.47) | HPGDNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL8776979 | 0.83 | KCNH2 (0.63) | KCNH2ALDH1A1LMNASIGMAR1TRPV1 | |
| SCHEMBL28534367 | 0.81 | KCNH2 (0.61) | KCNH2ALDH1A1LMNASIGMAR1TRPV1 | |
| SCHEMBL13997210 | 0.81 | CA1 (0.45) | HPGDNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL28525880 | 0.81 | KCNH2 (0.61) | KCNH2ALDH1A1LMNASIGMAR1TRPV1 | |
| SCHEMBL13133431 | 0.81 | RARB (0.55) | HPGDNPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020076632-A1 | High mobility charge transporting molecules for a charge transport layer | XEROX CORPORATION | 2002-06-20 | — | — | US | disclosed |