Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 12/20 | 0.58 |
| ▸ | OXTR | P30559 | 11/20 | 0.58 |
| ▸ | AVPR2 | P30518 | 10/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44381 | 0.84 | AVPR1A (0.53) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL4835384 | 0.83 | AVPR1A (0.83) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL4837407 | 0.76 | AVPR1A (0.90) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL38380 | 0.76 | AVPR1A (0.88) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL4697681 | 0.74 | AVPR1A (0.79) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL38725 | 0.74 | AVPR1A (0.47) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL4696235 | 0.73 | AVPR1A (0.77) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL2598091 | 0.73 | AVPR1A (1.00) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL4835403 | 0.73 | AVPR1A (0.85) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL31737367 | 0.73 | AVPR1A (1.00) | AVPR1AOXTRAVPR2CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147889-A1 | METHODS AND PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF A FEEDING DISORDER WITH EARLY-ONSET IN A PATIENT | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2011-12-01 | — | — | WO | disclosed |