Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 9/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 14/20 | 0.45 |
| ▸ | OXTR | P30559 | 8/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL39021 | 0.89 | AVPR1A (0.47) | AVPR1AAVPR2OXTRCHRM2CHRM4 | |
| SCHEMBL38603 | 0.78 | AVPR2 (0.58) | AVPR1AAVPR2OXTR | |
| Iodide SCHEMBL1660507 | 0.74 | AVPR2 (0.42) | AVPR1AAVPR2OXTRCHRM2CHRM4 | |
| SCHEMBL45767 | 0.74 | AVPR1A (0.58) | AVPR1AAVPR2OXTRCHRM2CHRM4 | |
| SCHEMBL44381 | 0.74 | AVPR1A (0.53) | AVPR1AAVPR2OXTRCHRM2CHRM4 | |
| SCHEMBL6425099 | 0.67 | AVPR1A (0.88) | AVPR1AAVPR2OXTRCHRM2CHRM4 | |
| SCHEMBL1660631 | 0.67 | OXTR (0.76) | AVPR1AAVPR2OXTRCHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL4829058 | 0.67 | AVPR1A (0.87) | AVPR1AAVPR2OXTRCHRM2CHRM4 | |
| SCHEMBL6204681 | 0.65 | AVPR1A (0.69) | AVPR1AAVPR2OXTRCHRM2CHRM4 | |
| Iodide SCHEMBL6202511 | 0.65 | AVPR1A (0.68) | AVPR1AAVPR2OXTRCHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2575853-A1 | METHODS AND PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF A FEEDING DISORDER WITH EARLY-ONSET IN A PATIENT | INSERM - Institut National de la Santé et de la Recherche Médicale (FR) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011147889-A1 | METHODS AND PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF A FEEDING DISORDER WITH EARLY-ONSET IN A PATIENT | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2011-12-01 | — | — | WO | disclosed |