Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | GRM5 | P41594 | 3/20 | 0.49 |
| ▸ | PTPRC | P08575 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.48 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.48 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27178358 | 0.88 | HNF4A (0.62) | HNF4APTPRCPTPN11 | |
| SCHEMBL14252110 | 0.84 | HNF4A (0.54) | HNF4AGRM5HAO1 | |
| SCHEMBL542005 | 0.84 | HNF4A (0.73) | HNF4AGRM5PTPN11 | |
| SCHEMBL20503723 | 0.84 | HNF4A (0.60) | HNF4ACA12CA2CA9CA1 | |
| SCHEMBL21679889 | 0.84 | HNF4A (0.60) | HNF4ACA12CA2CA9CA1 | |
| SCHEMBL27178395 | 0.82 | HNF4A (0.63) | HNF4ACA12CA2CA9CA1 | |
| SCHEMBL3640785 | 0.81 | CA12 (0.55) | HNF4ACA12CA2CA9CA1 | |
| SCHEMBL4578158 | 0.81 | CA12 (0.51) | CA12CA2CA9CA1GRM5 | |
| SCHEMBL28788080 | 0.81 | CA12 (0.55) | HNF4ACA12CA2CA9CA1 | |
| SCHEMBL9885470 | 0.80 | PTPN1 (0.59) | HNF4AGRM5PTPRCPTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1586569-B1 | Aryl ethynyl phthalic acid derivative and method for producing the same | FUJIFILM CORP (JP) | 2012-06-06 | — | — | EP | disclosed |
| US-7339071-B2 | Aryl ethynyl phthalic acid derivative and method for producing the same | FUJIFILM CORPORATION (JP) | 2008-03-04 | — | — | US | disclosed |
| US-7339071-B2 | Aryl ethynyl phthalic acid derivative and method for producing the same | FUJIFILM CORPORATION (JP) | 2008-03-04 | — | — | US | disclosed |
| EP-1586569-A1 | Aryl ethynyl phthalic acid derivative and method for producing the same | FUJI PHOTO FILM CO., LTD. (JP) | 2005-10-19 | — | — | EP | disclosed |
| US-20050215820-A1 | Aryl ethynyl phthalic acid derivative and method for producing the same | FUJI PHOTO FILM CO., LTD. | 2005-09-29 | — | — | US | disclosed |