Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 5/20 | 0.44 |
| ▸ | CES1 | P23141 | 5/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL2020364 | 0.87 | TSHR (0.61) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL6053894 | 0.87 | TSHR (0.61) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL6053600 | 0.87 | TSHR (0.61) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL5081356 | 0.85 | TSHR (0.54) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL29006820 | 0.85 | MAPK1 (0.40) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL27538027 | 0.84 | TSHR (0.52) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL26104752 | 0.82 | TSHR (0.42) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28321148 | 0.82 | TSHR (0.50) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL11514559 | 0.81 | TSHR (0.54) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28737090 | 0.81 | TSHR (0.54) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290625-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118290624-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118290623-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-117756970-A | Catalyst for butene-1 polymerization and application thereof | 中国石油化工股份有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-115975075-A | Catalyst component for olefin polymerization, catalyst and application | 中国石油化工股份有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-113444189-A | Catalyst for olefin polymerization and application thereof | 中国石油化工股份有限公司 | 2021-09-28 | — | — | CN | claimed |
| CN-106687513-B | Polymer compositions with improved noise suppression | 伊士曼化工公司 | 2020-02-07 | — | — | CN | claimed |
| EP-3059264-B1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PREPARATION METHOD THEREOF, AND CATALYST COMPRISING SAME | CHINA PETROLEUM & CHEM CORP (CN) | 2018-12-26 | — | — | EP | claimed |
| EP-3194483-B1 | POLYMERIC COMPOSITIONS WITH IMPROVED NOISE SUPPRESSION | EASTMAN CHEM CO (US) | 2018-12-19 | — | — | EP | claimed |
| EP-3194483-A1 | POLYMERIC COMPOSITIONS WITH IMPROVED NOISE SUPPRESSION | Eastman Chemical Company (US) | 2017-07-26 | — | — | EP | claimed |
| US-20160264694-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PREPARATION METHOD THEREOF, AND CATALYST COMPRISING SAME | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2016-09-15 | — | — | US | claimed |
| EP-3059264-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PREPARATION METHOD THEREOF, AND CATALYST COMPRISING SAME | China Petroleum&Chemical Corporation (CN) | 2016-08-24 | — | — | EP | claimed |
| WO-2016044230-A1 | POLYMERIC COMPOSITIONS WITH IMPROVED NOISE SUPPRESSION | EASTMAN CHEMICAL COMPANY (US) | 2016-03-24 | — | — | WO | claimed |
| US-20160075857-A1 | POLYMERIC COMPOSITIONS WITH IMPROVED NOISE SUPPRESSION | EASTMAN CHEMICAL COMPANY (US) | 2016-03-17 | — | — | US | claimed |
| WO-2025020304-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST AND USE OF CATALYST | 中国石油天然气股份有限公司 | 2025-01-30 | — | — | WO | disclosed |
| CN-118290624-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-118290623-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-1566164-A | Propene polymers and preparation process thereof | SINOPEC CORP (CN) | 2005-01-19 | — | — | CN | disclosed |
| EP-1472293-A1 | SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF | China Petroleum & Chemical Corporation (CN) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003068828-A1 | SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2003-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075857-A1 | POLYMERIC COMPOSITIONS WITH IMPROVED NOISE SUPPRESSION | LRBA, FARSB, PUF60 | TSHR 4848/4885DAO 4445/4885NAPRT 1811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.