Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4577849 | 1.00 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2MAPTPOLB | |
| Nocazoline A SCHEMBL27972241 | 0.84 | HTR2B (0.53) | NPC1RAB9ASMN1; SMN2MAPTPOLB | |
| Nocazoline A SCHEMBL27972242 | 0.84 | HTR2B (0.53) | NPC1RAB9ASMN1; SMN2MAPTPOLB | |
| Nocazoline A SCHEMBL31429548 | 0.84 | HTR2B (0.53) | NPC1RAB9ASMN1; SMN2MAPTPOLB | |
| Nocazoline A SCHEMBL27972281 | 0.84 | HTR2B (0.53) | NPC1RAB9ASMN1; SMN2MAPTPOLB | |
| Nocazoline A SCHEMBL29591840 | 0.84 | HTR2B (0.53) | NPC1RAB9ASMN1; SMN2MAPTPOLB | |
| SCHEMBL7803650 | 0.83 | POLB (0.38) | NPC1RAB9ASMN1; SMN2MAPTPOLB | |
| SCHEMBL28685759 | 0.82 | MAPT (0.66) | NPC1RAB9ASMN1; SMN2MAPTPOLB | |
| SCHEMBL28694392 | 0.82 | MAPT (0.66) | NPC1RAB9ASMN1; SMN2MAPTPOLB | |
| SCHEMBL27866967 | 0.82 | MAPT (0.66) | NPC1RAB9ASMN1; SMN2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1699784-A4 | NOVEL OXAZOLIDINONE DERIVATIVES | DONG A PHARM CO LTD (KR) | 2008-09-03 | — | — | EP | disclosed |
| EP-1699784-A1 | NOVEL OXAZOLIDINONE DERIVATIVES | Dong-A Pharmaceutical Co., Ltd. (KR) | 2006-09-13 | — | — | EP | disclosed |
| WO-2005058886-A1 | NOVEL OXAZOLIDINONE DERIVATIVES | DONG-A PHARM.CO.,LTD. (KR) | 2005-06-30 | — | — | WO | disclosed |