Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27866967 | 1.00 | MAPT (0.66) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL28694392 | 1.00 | MAPT (0.66) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL12786229 | 0.84 | MAPT (0.71) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL1983682 | 0.84 | MAPT (0.71) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL27868037 | 0.84 | MAPT (0.59) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL14448351 | 0.84 | MAPT (0.59) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL4577849 | 0.82 | NPC1 (0.43) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL4577847 | 0.82 | NPC1 (0.43) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL27259774 | 0.80 | MAPT (0.80) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL27866966 | 0.78 | NOS2 (0.41) | MAPTNPC1POLBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707848-A | Water-containing salicylaldehyde diamine oxazoline compound and metal complex thereof, and preparation method and application thereof | 浙江大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-114085250-B | Preparation and application of P-chiral phosphine-oxazoline ligand metal complex catalyst containing Ugi's amine building block | 中国人民解放军空军军医大学 | 2024-01-19 | — | — | CN | disclosed |
| CN-114085250-A | Preparation and application of P-chiral phosphine-oxazoline ligand metal complex catalyst containing Ugi's amine building blocks | 中国人民解放军空军军医大学 | 2022-02-25 | — | — | CN | disclosed |