Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 12/20 | 0.74 |
| ▸ | THRA | P10827 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | ACR | P10323 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192518 | 0.96 | THRB (0.68) | THRBTHRAKMT2AMEN1MAPT | |
| SCHEMBL14192452 | 0.96 | THRB (0.68) | THRBTHRAKMT2AMEN1MAPT | |
| SCHEMBL4578159 | 0.91 | THRB (0.76) | THRBTHRAKMT2AMEN1MAPT | |
| SCHEMBL3613955 | 0.90 | THRB (0.82) | THRBTHRAKMT2AMEN1MAPT | |
| SCHEMBL14192345 | 0.89 | THRB (0.62) | THRBTHRAKMT2AMEN1MAPT | |
| SCHEMBL10633416 | 0.88 | THRB (0.62) | THRBKMT2AMAPTSMN1; SMN2PLA2G1B | |
| SCHEMBL30354554 | 0.88 | THRB (0.62) | THRBKMT2AMAPTSMN1; SMN2PLA2G1B | |
| SCHEMBL14192438 | 0.87 | THRB (0.71) | THRBTHRAKMT2AMEN1MAPT | |
| SCHEMBL4904680 | 0.86 | THRB (1.00) | THRBTHRAKMT2AMEN1MAPT | |
| SCHEMBL14400631 | 0.86 | THRB (0.76) | THRBTHRAKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |
| US-20050012070-A1 | Liquid-crystalline vinyl ketone derivatives and their polymers | JNC PETROCHEMICAL CORPORATION (JP) | 2005-01-20 | — | — | US | disclosed |