SCHEMBL457799

SCHEMBL457799

Clc1c[c]cc(Br)c1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL458414 0.85
SCHEMBL96258 0.78
SCHEMBL2283688 0.78
SCHEMBL10809899 0.74
SCHEMBL20600844 0.74
SCHEMBL2286037 0.74
SCHEMBL2291564 0.74
SCHEMBL1355907 0.73
SCHEMBL11359647 0.69 CYP3A4 (0.32)
SCHEMBL2286239 0.69 POLB (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240043385-A1 ANTHELMINTIC COMPOUNDS COMPRISING A PYRIDINE STRUCTURE INTERVET INC. (US) 2024-02-08 US disclosed
US-20240043446-A1 ANTHELMINTIC COMPOUNDS COMPRISING A THIENOPYRIDINE STRUCTURE INTERVET INC. (US) 2024-02-08 US disclosed
US-20230148316-A1 ANTHELMINTIC COMPOUNDS COMPRISING A QUINOLINE STRUCTURE INTERVET INC. (US) 2023-05-11 US disclosed
US-20230110397-A1 ANTHELMINTIC COMPOUNDS COMPRISING AZAINDOLES STRUCTURE INTERVET INC. (US) 2023-04-13 US disclosed
EP-4077322-A1 ANTHELMINTIC COMPOUNDS COMPRISING AZAINDOLES STRUCTURE Intervet International B.V. (NL) 2022-10-26 EP disclosed
CN-114846014-A Insect repellent compounds comprising azaindole structures 英特维特国际股份有限公司 2022-08-02 CN disclosed
CN-114845994-A Insect-repellent compound comprising quinoline structure 英特维特国际股份有限公司 2022-08-02 CN disclosed
CN-114423748-A Novel heteroaryl triazole compounds as pesticides 拜耳公司 2022-04-29 CN disclosed
WO-2021122906-A1 ANTHELMINTIC COMPOUNDS COMPRISING AZAINDOLES STRUCTURE INTERVET INTERNATIONAL B.V. (NL) 2021-06-24 WO disclosed
EP-2927218-B1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2018-07-04 EP disclosed
US-7989394-B2 Substituted 1-(azolin-2-yl)-amino-2-aryl-1-hetaryl-ethane compounds BASF SE (DE) 2011-08-02 US disclosed
US-20090131256-A1 Substituted 1-(azolin-2-yl)-amino-2-aryl-1-hetaryl-ethane Compounds BASF SE (DE) 2009-05-21 US disclosed
US-4698333-A Use of substituted malonic acid derivatives as agents for combating pests BAYER AKTIENGESELLSCHAFT (DE) 1987-10-06 US disclosed
EP-0118833-B1 SUBSTITUTED DIAMIDES OF PHENYLHYDROXY-THIOMALONIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES BAYER AG (DE) 1986-04-02 EP disclosed
US-4562185-A INSECTICIDES; MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 1985-12-31 US disclosed
US-4556649-A Substituted malonic acid diamide insecticides, compositions and use BAYER AKTIENGESELLSCHAFT (DE) 1985-12-03 US disclosed
EP-0148499-A2 Substituted derivatives of malonic acid, process for their preparation and their use as pesticides BAYER AG (DE) 1985-07-17 EP disclosed
EP-0126235-A1 Five-membered nitrogen-containing heterocycles, process for their preparation and their use as pesticides BAYER AG (DE) 1984-11-28 EP disclosed
EP-0118833-A1 Substituted diamides of phenylhydroxy-thiomalonic acids, process for their preparation and their use as pesticides BAYER AG (DE) 1984-09-19 EP disclosed
EP-0108351-A2 Use of substituted malonic-acid derivatives as pesticides BAYER AG (DE) 1984-05-16 EP disclosed