⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2283688 | 0.85 | — | — | |
| SCHEMBL441763 | 0.81 | — | — | |
| SCHEMBL2291121 | 0.81 | — | — | |
| SCHEMBL2288263 | 0.75 | — | — | |
| SCHEMBL2282139 | 0.75 | GABRA1 (0.38) | — | |
| SCHEMBL27754364 | 0.75 | PNMT (0.37) | — | |
| SCHEMBL457799 | 0.73 | — | — | |
| SCHEMBL96258 | 0.72 | — | — | |
| SCHEMBL2291564 | 0.69 | — | — | |
| SCHEMBL10809899 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026089-B | Isoxazoline substituted benzamides and analogs as pesticides | 先正达参股股份有限公司 | 2021-10-22 | — | — | CN | claimed |
| EP-3353171-B1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDES AND ANALOGUES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-09-15 | — | — | EP | claimed |
| US-20210163459-A1 | PESTICIDALLY ACTIVE AZETIDINE SULFONES AMIDE ISOXAZOLINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2021-06-03 | — | — | US | claimed |
| EP-3810605-A1 | PESTICIDALLY ACTIVE AZETIDINE SULFONES AMIDE ISOXAZOLINE DERIVATIVES | Syngenta Crop Protection AG (CH) | 2021-04-28 | — | — | EP | claimed |
| US-10588317-B2 | Isoxazoline-substituted benzamides and analogues as insecticides | SYNGENTA PARTICIPATIONS AG (CH) | 2020-03-17 | — | — | US | claimed |
| EP-3601275-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2020-02-05 | — | — | EP | claimed |
| US-20200031817-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-01-30 | — | — | US | claimed |
| WO-2019243262-A1 | PESTICIDALLY ACTIVE AZETIDINE SULFONES AMIDE ISOXAZOLINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2019-12-26 | — | — | WO | claimed |
| WO-2018172477-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-09-27 | — | — | WO | claimed |
| US-20180255780-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDES AND ANALOGUES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-09-13 | — | — | US | claimed |
| US-6159973-A | Aromatic amides, their preparation process, the compositions containing them and their use as pesticides | HOECHST SCHERING AGREVO S.A. (FR) | 2000-12-12 | — | — | US | claimed |
| EP-0805795-B1 | NOVEL AROMATIC AMIDES, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS PESTICIDES | HOECHST SCHERING AGREVO SA (FR) | 2000-08-23 | — | — | EP | claimed |
| US-6013837-A | E.G.,4-(2-(3,4,5-TRICHLORO PHENYL) 1-FLUOROCYCLOPROPYL)-N-(2-METHYL PHENYL)BENZAMIDE; PARTICULAR USE AGAINST ARTHROPODS, HELMINTHS AND MOLLUSCS; INSECTICIDES; ACARICIDES; NEMATICIDES; PHOTOSTABILITY; NONTOXIC TO MAMMALS | HOECHST MARION ROUSSEL (FR) | 2000-01-11 | — | — | US | claimed |
| US-5965491-A | PESTICIDES OR AS INTERMEDIATES TO MAKE OTHER PESTICIDES; FOR CONTROL OF ARTHROPOD PESTS | RHONE-POULENC INC. (US) | 1999-10-12 | — | — | US | claimed |
| EP-0805795-A1 | NOVEL AROMATIC AMIDES, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS PESTICIDES | Hoechst Schering AgrEvo S.A. (FR) | 1997-11-12 | — | — | EP | claimed |
| WO-1996022965-A1 | NOVEL AROMATIC AMIDES, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS PESTICIDES | HOECHST SCHERING AGREVO S.A. (FR) | 1996-08-01 | — | — | WO | claimed |
| EP-0002895-B1 | ENZYME INHIBITORY PHTHALAZIN-4-YLACETIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND PROCESS FOR THEIR MANUFACTURE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-10-14 | — | — | EP | claimed |
| US-4251528-A | ALDOSE REDUCTASE INHIBITORS USEFUL IN DIABETES, GALACTOSEMIA | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-02-17 | — | — | US | claimed |
| EP-0002895-A1 | Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof, and process for their manufacture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-07-11 | — | — | EP | claimed |
| US-4073783-A | PENICILLINS | PFIZER INC. (US) | 1978-02-14 | — | — | US | claimed |