Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 8/20 | 0.42 |
| ▸ | PPARG | P37231 | 7/20 | 0.42 |
| ▸ | CTSK | P43235 | 8/20 | 0.41 |
| ▸ | CTSS | P25774 | 5/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4162336 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2PPARAPPARGCTSKCTSS | |
| SCHEMBL703741 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2PPARAPPARGCTSKCTSS | |
| SCHEMBL1645172 | 0.88 | SMN1; SMN2 (0.45) | SMN1; SMN2PPARAPPARGCTSKCTSS | |
| SCHEMBL1645174 | 0.88 | SMN1; SMN2 (0.45) | SMN1; SMN2PPARAPPARGCTSKCTSS | |
| SCHEMBL1940630 | 0.87 | CTSK (0.46) | SMN1; SMN2PPARAPPARGCTSKCTSS | |
| SCHEMBL14031160 | 0.87 | CTSK (0.46) | SMN1; SMN2PPARAPPARGCTSKCTSS | |
| SCHEMBL1940631 | 0.87 | CTSK (0.46) | SMN1; SMN2PPARAPPARGCTSKCTSS | |
| SCHEMBL13925030 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2CTSKCTSSGAAKMT2A | |
| SCHEMBL13925029 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2CTSKCTSSGAAKMT2A | |
| SCHEMBL1943040 | 0.85 | CTSK (0.48) | SMN1; SMN2PPARAPPARGCTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112689507-A | Amino acid compounds having unbranched linkers and methods of use thereof | 普利安特治疗公司 | 2021-04-20 | — | — | CN | disclosed |
| EP-1824816-A4 | A NOVEL PROCESS FOR THE PREPARATION OF NONRACEMIC LONG CHAIN alpha-AMINO ACIDS DERIVATIVES | WUXI PHARMA TECH CO LTD (CN) | 2008-01-02 | — | — | EP | disclosed |
| EP-1824816-A1 | A NOVEL PROCESS FOR THE PREPARATION OF NONRACEMIC LONG CHAIN alpha-AMINO ACIDS DERIVATIVES | Wuxi Pharma Tech Co., Ltd. (CN) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006039841-A1 | A NOVEL PROCESS FOR THE PREPARATION OF NONRACEMIC LONG CHAIN α-AMINO ACIDS DERIVATIVES | WUXI PHARMA TECH CO., LTD. (CN) | 2006-04-20 | — | — | WO | disclosed |