SCHEMBL4578627

SCHEMBL4578627

OC(CSc1ccccc1)CN1CCN(CC(O)CSc2ccccc2)CC1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.68
L3MBTL1 Q9Y468 2/20 0.50
ADRA2A P08913 1/20 0.50
ADRA2B P18089 1/20 0.50
ADRA2C P18825 1/20 0.50
KDM4E B2RXH2 2/20 0.48
POLB P06746 1/20 0.47
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
OPRM1 P35372 1/20 0.46
OPRD1 P41143 1/20 0.46
LMNA P02545 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
GPR55 Q9Y2T6 1/20 0.45
HSD17B10 Q99714 1/20 0.44
ALDH1A1 P00352 1/20 0.44
CYP2D6 P10635 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11719282 1.00 MAPT (0.68) MAPTL3MBTL1ADRA2AADRA2BADRA2C
SCHEMBL9142228 0.92 MAPT (0.60) MAPTL3MBTL1ADRA2AADRA2BADRA2C
Hydrochloric Acid SCHEMBL11590808 0.91 MAPT (0.59) MAPTL3MBTL1ADRA2AADRA2BADRA2C
Hydrochloric Acid SCHEMBL11591663 0.90 MAPT (0.58) MAPTL3MBTL1KDM4EPOLBMEN1
SCHEMBL9142116 0.89 KMT2A (0.64) MAPTMEN1KMT2AOPRM1OPRD1
SCHEMBL6537026 0.89 MAPT (0.56) MAPTL3MBTL1ADRA2AADRA2BADRA2C
SCHEMBL9140220 0.87 MAPT (0.55) MAPTPOLBMEN1KMT2AOPRM1
SCHEMBL9142386 0.85 MAPT (0.53) MAPTPOLBMEN1KMT2AGAA
SCHEMBL9142663 0.84 MAPT (0.68) MAPTADRA2AADRA2BADRA2CKDM4E
SCHEMBL7279492 0.83 SMN1; SMN2 (0.56) MAPTKDM4EPOLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1298490-B1 Photopolymerizable composition and recording material FUJIFILM CORP (JP) 2008-08-13 EP disclosed
US-7399569-B2 Method for producing microcapsules, microcapsules, recording material, and heat-sensitive recording material FUJIFILM CORPORATION (JP) 2008-07-15 US disclosed
US-7300738-B2 Azolinyl acetic acid derivative and azolinyl acetic acid derivative containing recording material FUJIFILM CORPORATION (JP) 2007-11-27 US disclosed
US-7220529-B2 Photopolymerizable composition and recording material using the same FUJIFILM CORPORATION (JP) 2007-05-22 US disclosed
US-7205083-B2 Recording material FUJIFILM CORPORATION (JP) 2007-04-17 US disclosed
EP-1254780-B1 Recording material FUJI PHOTO FILM CO LTD (JP) 2007-01-03 EP disclosed
US-7157407-B2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 2007-01-02 US disclosed
US-7118844-B2 Diazonium salt and thermal recording material using the same FUJI PHOTO FILM CO., LTD. (JP) 2006-10-10 US disclosed
US-7094731-B2 Recording material FUJI PHOTO FILM CO., LTD. (JP) 2006-08-22 US disclosed
EP-1253466-B1 Diazonium salt and heat-sensitive recording material FUJI PHOTO FILM CO LTD (JP) 2006-05-31 EP disclosed
EP-0930529-A1 Heat-sensitive recording material Fuji Photo Film., Ltd. (JP) 1999-07-21 EP disclosed
US-5925489-A CONTAINING DIAZONIUM SALT AND PYRROLOPYRIMIDINE COUPLER WHICH REACT WHEN HEATED TO DEVELOP VIOLET TO CYAN COLORS, IMAGE QUALITY AND STABILITY, SHELF LIFE FUJI PHOTO FILM CO., LTD. (JP) 1999-07-20 US disclosed
US-5866293-A CONTAINING DIAZO COMPOUND AND PYRAZOLONE COUPLER; STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1999-02-02 US disclosed
EP-0827020-A1 Thermal recording material FUJI PHOTO FILM CO., LTD. (JP) 1998-03-04 EP disclosed
EP-0809145-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1997-11-26 EP disclosed
US-5683850-A HAVING EXCELLENT RAW STOCK STORABILITY AND IMAGE STORAGE CHARACTERISTICS FUJI PHOTO FILM CO., LTD. (JP) 1997-11-04 US disclosed
US-5543260-A RED COLOR; STORAGE STABILITY; COLORFASTNESS FUJI PHOTO FILM CO., LTD. (JP) 1996-08-06 US disclosed
US-5236800-A Support; diazo compound; no solvnet; coupling component; basic substance; shelf life FUJI PHOTO FILM CO., LTD. (JP) 1993-08-17 US disclosed
US-5213939-A Having recording layer containing 1-disubstituted amino-3-alkoxybenzene-4-diazonnium salt, cyclohexanone derivative as coupling compound and organic base, storage stable, magenta color, low temperature development FUJI PHOTO FILM CO., LTD. (JP) 1993-05-25 US disclosed
US-4975353-A Support and layer of diazo compound, coupling component for coloration and basic compound FUJI PHOTO FILM CO., LTD. (JP) 1990-12-04 US disclosed