Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.64 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | IGF1R | P08069 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9142663 | 0.91 | MAPT (0.68) | KMT2AMEN1OPRM1OPRD1MAPT | |
| SCHEMBL11719282 | 0.89 | MAPT (0.68) | KMT2AMEN1OPRM1OPRD1MAPT | |
| SCHEMBL4578627 | 0.89 | MAPT (0.68) | KMT2AMEN1OPRM1OPRD1MAPT | |
| SCHEMBL9142228 | 0.88 | MAPT (0.60) | KMT2AMEN1OPRM1OPRD1MAPT | |
| SCHEMBL9140220 | 0.83 | MAPT (0.55) | KMT2AMEN1OPRM1OPRD1MAPT | |
| SCHEMBL9572466 | 0.82 | MAPT (0.60) | KMT2AMEN1OPRM1OPRD1MAPT | |
| SCHEMBL7279486 | 0.82 | MAPT (0.51) | KMT2AMEN1OPRM1OPRD1MAPT | |
| SCHEMBL9142386 | 0.81 | MAPT (0.53) | KMT2AMEN1MAPTGAA | |
| Hydrochloric Acid SCHEMBL11590808 | 0.81 | MAPT (0.59) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL11591663 | 0.81 | MAPT (0.58) | KMT2AMEN1MAPTCYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391552-A | Has strong antagonism against calcium with less side effects | POLA CHEMICAL INDUSTRIES, INC. (JP) | 1995-02-21 | — | — | US | disclosed |
| EP-0612738-A1 | Diphenylpiperazine derivative and drug for circulatory organ containing the same | POLA CHEMICAL INDUSTRIES, INC. (JP) | 1994-08-31 | — | — | EP | disclosed |
| EP-0549796-A1 | DIPHENYLPIPERAZINE DERIVATIVE AND DRUG FOR CIRCULATORY ORGAN CONTAINING THE SAME | POLA CHEMICAL INDUSTRIES INC (JP) | 1993-07-07 | — | — | EP | disclosed |