SCHEMBL457883

SCHEMBL457883

CC(C)(O)CC#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL17800994 1.00
Acetic Acid SCHEMBL8752671 0.87 FFAR3 (0.35)
SCHEMBL3341220 0.81
Dimethylformamide SCHEMBL8084521 0.81 TSHR (0.39)
SCHEMBL2973761 0.80
Methyl Alcohol SCHEMBL4608132 0.73 ALDH1A1 (0.33)
SCHEMBL5590844 0.73
SCHEMBL16889132 0.73
SCHEMBL3499736 0.73
SCHEMBL16889133 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 535 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115851685-B Nitrilase and application thereof in synthesis of 3-hydroxy-3-methylbutyric acid 万华化学集团股份有限公司 2025-04-01 CN claimed
US-12162828-B2 Process for preparing 3-hydroxy-3-methylbutyric acid (HMB) and salts thereof EVONIK OPERATIONS GMBH (DE) 2024-12-10 US claimed
CN-118348146-A HPLC detection method for migration amount of simethicone in medicine 南京臣功制药股份有限公司 2024-07-16 CN claimed
CN-117420245-A Detection method of human dry blood spot ceramide and kit for detecting ceramide 南京品生医学检验实验室有限公司 2024-01-19 CN claimed
CN-117088911-A Method for separating PE from breast milk extracellular vesicles and application of PE in preparation of medicines for preventing and treating obesity 上海市同仁医院 2023-11-21 CN claimed
CN-117030871-A Method for detecting palmitic acid in paliperidone palmitate 济南辰欣医药科技有限公司 2023-11-10 CN claimed
CN-114561210-B Zn-Cu-In-S quantum sheet, solar cell, and preparation method and application thereof 青岛大学 2023-10-13 CN claimed
US-20230312486-A1 POLYMORPHIC FORMS OF A ROR INHIBITING COMPOUND AND PROCESSES FOR ITS PREPARATION GLENMARK SPECIALTY S.A. (CH) 2023-10-05 US claimed
CN-116688563-A Composite extractant, pretreatment method for detecting estrone in blood and detection method for detecting estrone in blood 浙江省疾病预防控制中心 2023-09-05 CN claimed
CN-116500180-A LC-MS/MS-based ceramide chromatographic characteristic prediction and characterization method 上海大学 2023-07-28 CN claimed
WO-2015052568-A2 SOLID FORMS OF CURCUMIN AND DERIVATIVES THEREOF LAURUS LABS PRIVATE LIMITED (IN) 2015-04-16 WO claimed
US-20040142946-A1 Modified nucleosides and nucleotides and use thereof CHATTOPADHYAYA JYOTI (SE) 2004-07-22 US claimed
EP-1332150-A1 MODIFIED NUCLEOSIDES AND NUCLEOTIDES AND USE THEREOF Chattopadhyaya, Jyoti (SE) 2003-08-06 EP claimed
WO-2002038578-A1 MODIFIED NUCLEOSIDES AND NUCLEOTIDES AND USE THEREOF CHATTOPADHYAYA JYOTI (SE) 2002-05-16 WO claimed
US-6022977-A Dynamic resolution of isoxazoline thioesters to isoxazoline carboxylic acids DUPONT PHARMACEUTICALS COMPANY (US) 2000-02-08 US claimed
EP-0971906-A1 LIPASE CATALYZED DYNAMIC RESOLUTION OF ISOXAZOLINE THIOESTERS TO ISOXAZOLINE CARBOXYLIC ACIDS Du Pont Pharmaceuticals Company (US) 2000-01-19 EP claimed
WO-1998042687-A1 LIPASE CATALYZED DYNAMIC RESOLUTION OF ISOXAZOLINE THIOESTERS TO ISOXAZOLINE CARBOXYLIC ACIDS DU PONT PHARMACEUTICALS COMPANY (US) 1998-10-01 WO claimed
US-5721350-A Deuterated nucleosides CHATTOPADHYAYA JYOTI (SE) 1998-02-24 US claimed
EP-0648220-A1 DEUTERATED NUCLEOSIDES CHATTOPADHYAYA, Jyoti (SE) 1995-04-19 EP claimed
WO-1993025566-A1 DEUTERATED NUCLEOSIDES CHATTOPADHYAYA JYOTI (SE) 1993-12-23 WO claimed