Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.66 |
| ▸ | MEN1 | O00255 | 8/20 | 0.66 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | CCR6 | P51684 | 1/20 | 0.66 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | DDX3X | O00571 | 2/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.60 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10573661 | 0.86 | MEN1 (0.69) | KMT2AMEN1HSP90AA1HPGDNPSR1 | |
| SCHEMBL11574390 | 0.86 | KMT2A (0.63) | KMT2AMEN1HSP90AA1HPGDNPSR1 | |
| SCHEMBL11402843 | 0.84 | MAPT (0.63) | HPGDNPC1ALDH1A1MAPTPOLB | |
| SCHEMBL1126505 | 0.83 | KMT2A (0.67) | KMT2AMEN1HPGDPKMALDH1A1 | |
| SCHEMBL27972065 | 0.83 | MEN1 (0.60) | KMT2AMEN1HSP90AA1HPGDNPSR1 | |
| SCHEMBL10978787 | 0.82 | ALDH1A1 (0.65) | KMT2AMEN1HSP90AA1HPGDNPSR1 | |
| SCHEMBL11816127 | 0.81 | MEN1 (0.62) | KMT2AMEN1HSP90AA1HPGDNPSR1 | |
| SCHEMBL4742571 | 0.81 | DHODH (0.64) | KMT2AMEN1HSP90AA1HPGDNPSR1 | |
| SCHEMBL11453702 | 0.80 | MAPT (0.58) | KMT2AMEN1HPGDNPSR1NPC1 | |
| Hydrochloric Acid SCHEMBL11810360 | 0.80 | MEN1 (0.61) | KMT2AMEN1HSP90AA1HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435744-B2 | Piperidine derivatives as NMDA receptor antagonists | GEDEON RICHTER VEGYESZETI GYAR RT (HU) | 2008-10-14 | — | — | US | disclosed |
| US-20040157886-A1 | Piperdine derivatives as NMDA receptor antagonists | UCB Biopharma SRL (BE) | 2004-08-12 | — | — | US | disclosed |
| EP-1409477-A1 | PIPERIDINE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003010159-A1 | PIPERIDINE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-02-06 | — | — | WO | disclosed |
| US-4128660-A | Anti-allergic aminooxanilic acids and esters | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |
| US-4011337-A | ANTIALLERGENS | THE UPJOHN COMPANY (US) | 1977-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157886-A1 | Piperdine derivatives as NMDA receptor antagonists | GRIN1, GRIN2D, GRIN2C | KMT2A 1234/4885MEN1 2584/4885HSP90AA1 3733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.