Adenine

Adenine

SCHEMBL4579097

Cc1c[nH]c(=O)[nH]c1=O.Nc1cc[nH]c(=O)n1.Nc1ncnc2nc[nH]c12

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 3/20 0.46
PI4K2B Q8TCG2 3/20 0.46
PI4K2A Q9BTU6 3/20 0.46
PI4KB Q9UBF8 3/20 0.46
LMNA P02545 1/20 0.46
DRD3 P35462 1/20 0.46
XDH P47989 1/20 0.46
LRRK2 Q5S007 1/20 0.46
ATAD2 Q6PL18 1/20 0.40
PRMT1 Q99873 1/20 0.38
PNP P00491 1/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C19 P33261 1/20 0.34
RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenine SCHEMBL6227732 0.95 PI4KA (0.41) PI4KAPI4K2BPI4K2API4KBLMNA
Guanine SCHEMBL5097009 0.93 PNP (0.47) PI4KAPI4K2BPI4K2API4KBLMNA
Guanine SCHEMBL9468295 0.93 PNP (0.46) PI4KAPI4K2BPI4K2API4KBLMNA
Acenaphthene SCHEMBL20636763 0.89 PI4KA (0.37) PI4KAPI4K2BPI4K2API4KBLMNA
Guanine SCHEMBL15718981 0.89 PNP (0.43) PI4KAPI4K2BPI4K2API4KBLMNA
Guanine SCHEMBL9468227 0.89 PNP (0.43) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL906215 0.88 PI4KA (0.59) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL8860590 0.88 PI4KA (0.59) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL4633068 0.88 PI4KA (0.59) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL5580105 0.86 PI4KA (0.49) PI4KAPI4K2BPI4K2API4KBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118355122-A Aptamer for personal healthcare applications 宝洁公司 2024-07-16 CN claimed
US-20230287434-A1 APTAMERS FOR PERSONAL HEALTH CARE APPLICATIONS COMPANY, THE P&G, COMP 2023-09-14 US claimed
CN-118355122-A Aptamer for personal healthcare applications 宝洁公司 2024-07-16 CN disclosed
CN-118355123-A Aptamer for personal healthcare applications 宝洁公司 2024-07-16 CN disclosed
CN-118339295-A Aptamer for personal healthcare applications 宝洁公司 2024-07-12 CN disclosed
WO-2024006976-A2 TRANSFERRIN RECEPTOR BINDING MOLECULE CONJUGATES FOR DELIVERY OF OLIGONUCLEOTIDES TO CELLS DENALI THERAPEUTICS INC. (US) 2024-01-04 WO disclosed
US-20230340495-A1 APTAMERS FOR PERSONAL HEALTH CARE APPLICATIONS COMPANY, THE P&G 2023-10-26 US disclosed
EP-4263834-A1 APTAMERS FOR PERSONAL HEALTH CARE APPLICATIONS The Procter & Gamble Company (US) 2023-10-25 EP disclosed
EP-4263835-A1 APTAMERS FOR PERSONAL HEALTH CARE APPLICATIONS The Procter & Gamble Company (US) 2023-10-25 EP disclosed
US-20230313201-A1 APTAMERS FOR PERSONAL HEALTH CARE APPLICATIONS COMPANY, THE P&G, COMP 2023-10-05 US disclosed
US-20230287434-A1 APTAMERS FOR PERSONAL HEALTH CARE APPLICATIONS COMPANY, THE P&G, COMP 2023-09-14 US disclosed
US-20180171368-A1 PROCESS FOR THE BIOLOGICAL PRODUCTION OF METHACRYLIC ACID AND DERIVATIVES THEREOF Mitsubishi Chemical UK Limited (GB) 2018-06-21 US disclosed
EP-3298153-A1 PROCESS FOR THE BIOLOGICAL PRODUCTION OF METHACRYLIC ACID AND DERIVATIVES THEREOF Lucite International UK Limited (GB) 2018-03-28 EP disclosed
WO-2016185211-A1 PROCESS FOR THE BIOLOGICAL PRODUCTIION OF METHACRYLIC ACID AND DERIVATIVES THEREOF LUCITE INTERNATIONAL UK LIMITED (GB) 2016-11-24 WO disclosed
US-7319026-B2 Amino acid-producing bacteria and a process for preparing L-amino acids DEGUSSA AG (DE) 2008-01-15 US disclosed
EP-1481075-A2 AMINO ACID-PRODUCING BACTERIA AND A PROCESS FOR PREPARING L-AMINO ACIDS Degussa AG (DE) 2004-12-01 EP disclosed
US-20040082040-A1 Amino acid-producing bacteria and a process for preparing L-amino acids DEGUSSA AG 2004-04-29 US disclosed
WO-2003074719-A2 AMINO ACID-PRODUCING BACTERIA AND A PROCESS FOR PREPARING L-AMINO ACIDS DEGUSSA AG (DE) 2003-09-12 WO disclosed
EP-0986572-A2 IMMUNOSTIMULATORY OLIGONUCLEOTIDES, COMPOSITIONS THEREOF AND METHODS OF USE THEREOF Dynavax Technologies Corporation (US) 2000-03-22 EP disclosed
WO-1998055495-A2 IMMUNOSTIMULATORY OLIGONUCLEOTIDES, COMPOSITIONS THEREOF AND METHODS OF USE THEREOF DYNAVAX TECHNOLOGIES CORPORATION (US) 1998-12-10 WO disclosed