SCHEMBL3138532

SCHEMBL3138532

CCCN1C(=O)CSC1=S

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 8/20 0.56
GSK3B P49841 8/20 0.56
MEN1 O00255 6/20 0.55
KMT2A Q03164 6/20 0.55
GAA P10253 5/20 0.54
ALDH1A1 P00352 4/20 0.49
PAX8 Q06710 1/20 0.49
RECQL P46063 3/20 0.45
MAPT P10636 3/20 0.44
THRB P10828 2/20 0.44
HTT P42858 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
POLB P06746 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
HSD17B10 Q99714 2/20 0.43
LMNA P02545 1/20 0.43
TP53 P04637 1/20 0.43
ALOX15 P16050 1/20 0.43
MAPK1 P28482 1/20 0.43
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2788487 0.89 MEN1 (0.59) GSK3AGSK3BMEN1KMT2AGAA
SCHEMBL3062340 0.87 GSK3A (0.62) GSK3AGSK3BMEN1KMT2AGAA
SCHEMBL186221 0.87 MEN1 (0.62) GSK3AGSK3BMEN1KMT2AGAA
SCHEMBL28886326 0.85 MEN1 (0.65) GSK3AGSK3BMEN1KMT2AGAA
SCHEMBL19220386 0.85 MEN1 (0.65) GSK3AGSK3BMEN1KMT2AGAA
SCHEMBL16274020 0.85 MEN1 (0.65) GSK3AGSK3BMEN1KMT2AGAA
SCHEMBL26286 0.85 MEN1 (0.65) GSK3AGSK3BMEN1KMT2AGAA
SCHEMBL20176213 0.85 MEN1 (0.65) GSK3AGSK3BMEN1KMT2AGAA
SCHEMBL14850663 0.85 MEN1 (0.65) GSK3AGSK3BMEN1KMT2AGAA
SCHEMBL153669 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59125725-A None JP disclosed
WO-2023064368-A1 NOVEL RHODANINE DERIVATIVES AND USES THEREOF GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2023-04-20 WO disclosed
EP-2943584-B1 MACROPHAGE IDENTIFICATION AGENT, AND IDENTIFICATION METHOD, SORTING METHOD, EVALUATION METHOD, SCREENING METHOD AND KIT USING THE MACROPHAGE IDENTIFIER AGENT CANON KK (JP) 2019-08-14 EP disclosed
CN-108976222-A Biaryl Oxazolidinone compound containing heterocycle and preparation method thereof 沈阳药科大学 2018-12-11 CN disclosed
US-10041937-B2 Macrophage identification agent, and identification method, sorting method, evaluation method, screening method and kit using the macrophage identifier agent CANON KABUSHIKI KAISHA (JP) 2018-08-07 US disclosed
US-10041937-B2 Macrophage identification agent, and identification method, sorting method, evaluation method, screening method and kit using the macrophage identifier agent CANON KABUSHIKI KAISHA (JP) 2018-08-07 US disclosed
US-20160018389-A1 MACROPHAGE IDENTIFICATION AGENT, AND IDENTIFICATION METHOD, SORTING METHOD, EVALUATION METHOD, SCREENING METHOD AND KIT USING THE MACROPHAGE IDENTIFIER AGENT CANON KABUSHIKI KAISHA (JP) 2016-01-21 US disclosed
US-20160018389-A1 MACROPHAGE IDENTIFICATION AGENT, AND IDENTIFICATION METHOD, SORTING METHOD, EVALUATION METHOD, SCREENING METHOD AND KIT USING THE MACROPHAGE IDENTIFIER AGENT CANON KABUSHIKI KAISHA (JP) 2016-01-21 US disclosed
WO-2014192972-A1 MACROPHAGE IDENTIFICATION AGENT, AND IDENTIFICATION METHOD, SORTING METHOD, EVALUATION METHOD, SCREENING METHOD AND KIT USING THE MACROPHAGE IDENTIFIER AGENT CANON KABUSHIKI KAISHA (JP) 2014-12-04 WO disclosed
US-20120219613-A1 Novel Antiviral Agents for Enveloped Viruses THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-08-30 US disclosed
WO-2010044924-A1 NOVEL ANTIVIRAL AGENTS FOR ENVELOPED VIRUSES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-04-22 WO disclosed
JP-S59125725-A PHOTOPOLYMERIZABLE RESIN COMPOSITION MITSUBISHI RAYON CO LTD 1984-07-20 JP disclosed
US-4375508-A ACETHYLENIC HYDROCARBON CHAIN EASTMAN KODAK COMPANY (US) 1983-03-01 US disclosed
US-4283488-A SILVER HALIDE EMULSIONS EASTMAN KODAK COMPANY (US) 1981-08-11 US disclosed
US-4108667-A Photographic compositions and elements containing benzo[a]quinolizinium methine dyes EASTMAN KODAK COMPANY (US) 1978-08-22 US disclosed
US-4003750-A METHINE DYES EASTMAN KODAK COMPANY (US) 1977-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10041937-B2 Macrophage identification agent, and identification method, sorting method, evaluation method, screening method and kit using the macrophage identifier agent CD68, MSR1, MYADM GSK3A 4486/4885GSK3B 4706/4885MEN1 1787/4885
US-20120219613-A1 Novel Antiviral Agents for Enveloped Viruses MAVS, LAMP1, HAVCR2 GSK3A 4523/4885GSK3B 4599/4885MEN1 4512/4885
US-20160018389-A1 MACROPHAGE IDENTIFICATION AGENT, AND IDENTIFICATION METHOD, SORTING METHOD, EVALUATION METHOD, SCREENING METHOD AND KIT USING THE MACROPHAGE IDENTIFIER AGENT CD68, MSR1, MYADM GSK3A 4486/4885GSK3B 4706/4885MEN1 1787/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.