Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 2/20 | 0.47 |
| ▸ | GLI1 | P08151 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 4/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | PFKFB2 | O60825 | 1/20 | 0.32 |
| ▸ | PFKFB1 | P16118 | 1/20 | 0.32 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4579452 | 1.00 | SCN4A (0.47) | SCN4AGLI1PRCPNOS2NOS3 | |
| SCHEMBL14537859 | 0.86 | SCN4A (0.47) | SCN4AGLI1PRCPNOS2NOS3 | |
| SCHEMBL3330058 | 0.82 | SCN4A (0.49) | SCN4AGLI1PRCPNOS2NOS3 | |
| SCHEMBL3834069 | 0.82 | SCN4A (0.43) | SCN4AGLI1PRCPNOS2NOS3 | |
| SCHEMBL26716397 | 0.82 | SCN4A (0.43) | SCN4AGLI1PRCPNOS2NOS3 | |
| Hydrochloric Acid SCHEMBL3830057 | 0.81 | SCN4A (0.43) | SCN4AGLI1PRCPNOS2NOS3 | |
| SCHEMBL29772688 | 0.79 | SCN4A (0.47) | SCN4AGLI1PRCPNOS2NOS3 | |
| SCHEMBL8788154 | 0.79 | SCN4A (0.47) | SCN4AGLI1PRCPNOS2NOS3 | |
| SCHEMBL7749879 | 0.78 | SCN4A (0.46) | SCN4AGLI1PRCPNOS2NOS3 | |
| SCHEMBL7749876 | 0.78 | SCN4A (0.46) | SCN4AGLI1PRCPNOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951686-A1 | QUINAZOLINE DERIVATIVES AS A MULTIPLEX INHIBITOR AND METHOD FOR THE PREPARATION THEREOF | Hanmi Pharm. Co., Ltd. (KR) | 2008-08-06 | — | — | EP | claimed |
| WO-2007055514-A1 | QUINAZOLINE DERIVATIVES AS A MULTIPLEX INHIBITOR AND METHOD FOR THE PREPARATION THEREOF | HANMI PHARM. CO., LTD. (KR) | 2007-05-18 | — | — | WO | claimed |