Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 1/20 | 0.47 |
| ▸ | GLI1 | P08151 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 3/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29772688 | 1.00 | SCN4A (0.47) | SCN4AGLI1PRCPNOS2NOS3 | |
| SCHEMBL3330058 | 0.82 | SCN4A (0.49) | SCN4AGLI1PRCPNOS2NOS3 | |
| SCHEMBL3359438 | 0.82 | SCN4A (0.42) | SCN4AGLI1PRCPNOS2NOS3 | |
| SCHEMBL28367481 | 0.81 | SCN4A (0.41) | SCN4AGLI1PRCPNOS2NOS3 | |
| SCHEMBL14537859 | 0.79 | SCN4A (0.47) | SCN4AGLI1PRCPNOS2NOS3 | |
| SCHEMBL4579452 | 0.79 | SCN4A (0.47) | SCN4AGLI1PRCPNOS2NOS3 | |
| SCHEMBL4579448 | 0.79 | SCN4A (0.47) | SCN4AGLI1PRCPNOS2NOS3 | |
| Creatine SCHEMBL19284479 | 0.79 | NOS2 (0.45) | SCN4AGLI1PRCPNOS2NOS3 | |
| Creatine SCHEMBL19284478 | 0.79 | NOS2 (0.45) | SCN4AGLI1PRCPNOS2NOS3 | |
| SCHEMBL7749879 | 0.78 | SCN4A (0.46) | SCN4AGLI1PRCPNOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626942-B1 | BICYCLO[2.2.2.]OCTANE DERIVATIVES AS CHOLESTOCYSTOKININ INHIBITORS | BLACK JAMES FOUNDATION (GB) | 1997-04-23 | — | — | EP | disclosed |
| US-5514683-A | LIGANDS FKOR CHOLECYSTOKININ OR GASTRIN RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 1996-05-07 | — | — | US | disclosed |
| EP-0626942-A1 | BICYCLO 2.2.2.]OCTANE DERIVATIVES AS CHOLESTOCYSTOKININ INHIBITORS. | BLACK JAMES FOUNDATION (GB) | 1994-12-07 | — | — | EP | disclosed |
| WO-1993016982-A1 | BICYCLO[2.2.2.]OCTANE DERIVATIVES AS CHOLESTOCYSTOKININ INHIBITORS | JAMES BLACK FOUNDATION LIMITED (GB) | 1993-09-02 | — | — | WO | disclosed |