Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 13/20 | 0.44 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL711884 | 0.99 | CETP (0.43) | CETPNOTCH1GSK3AMEN1KMT2A | |
| SCHEMBL972797 | 0.91 | NOTCH1 (0.42) | CETPNOTCH1GSK3AMEN1KMT2A | |
| SCHEMBL971430 | 0.90 | NOTCH1 (0.41) | CETPNOTCH1GSK3AMEN1KMT2A | |
| SCHEMBL10038016 | 0.88 | ALDH1A1 (0.41) | GSK3AMEN1KMT2AGSK3BTSHR | |
| SCHEMBL4579496 | 0.88 | CETP (0.44) | CETPCCR1CCR2 | |
| SCHEMBL713237 | 0.86 | CETP (0.44) | CETPNOTCH1GSK3AMEN1KMT2A | |
| SCHEMBL4578818 | 0.85 | CETP (0.44) | CETPNOTCH1GSK3AMEN1KMT2A | |
| SCHEMBL972055 | 0.82 | GSK3A (0.39) | CETPNOTCH1GSK3AMEN1KMT2A | |
| SCHEMBL971304 | 0.81 | NOTCH1 (0.43) | CETPNOTCH1GSK3AMEN1KMT2A | |
| SCHEMBL973087 | 0.80 | NOTCH1 (0.47) | NOTCH1GSK3AMEN1KMT2ACCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194609-A1 | Chemical Compound and Its Use | BAYER HEATHCARE AG (DE) | 2008-08-14 | — | — | US | disclosed |
| US-20080194609-A1 | Chemical Compound and Its Use | BAYER HEATHCARE AG (DE) | 2008-08-14 | — | — | US | disclosed |
| US-20080194609-A1 | Chemical Compound and Its Use | BAYER HEATHCARE AG (DE) | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194609-A1 | Chemical Compound and Its Use | CETP, MTTP, LCAT | CETP 1/4885NOTCH1 2558/4885GSK3A 1106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.