⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL206082 | 0.83 | — | — | |
| SCHEMBL1868132 | 0.79 | TYR (0.35) | — | |
| SCHEMBL10509760 | 0.79 | — | — | |
| SCHEMBL7220933 | 0.78 | TAAR1 (0.36) | — | |
| SCHEMBL1866526 | 0.78 | GHSR (0.37) | — | |
| SCHEMBL27795007 | 0.77 | — | — | |
| SCHEMBL2073678 | 0.77 | — | — | |
| SCHEMBL4074532 | 0.77 | — | — | |
| SCHEMBL7220390 | 0.77 | SLC6A4 (0.36) | — | |
| SCHEMBL6977336 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836296-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-101851211-B | Piperazine amide compound | JIANGSU CHIA TAI TIANQING PHAR | 2013-08-14 | — | — | CN | claimed |
| EP-2513064-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING BIOFILMS | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2012-10-24 | — | — | EP | claimed |
| CN-102558074-A | Piperazine amide compound containing pyridazine substituent group | GUANGZHOU INST BIOMED & HEALTH | 2012-07-11 | — | — | CN | claimed |
| CN-102512421-A | Novel application of piperazine acidamide compound in pharmacy | GUANGZHOU INST BIOMED & HEALTH | 2012-06-27 | — | — | CN | claimed |
| WO-2011080132-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING BIOFILMS | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) | 2011-07-07 | — | — | WO | claimed |
| CN-101851211-A | Novel piperazine amide compound | JIANGSU CHIA TAI TIANQING PHAR | 2010-10-06 | — | — | CN | claimed |
| EP-2049490-A1 | N-(BENZOYL)-O- [2- (PYRIDIN- 2 -YLAMINO) ETHYL]-L-TYROSINE DERIVATIVES AND RELATED COMPOUNDS AS A5B1 ANTAGONISTS FOR THE TREATMENT OF SOLID TUMORS | Astra Zeneca AB (SE) | 2009-04-22 | — | — | EP | claimed |
| US-20080045521-A1 | PHENYLALANINE DERIVATIVES | ASTRAZENECA AB (SE) | 2008-02-21 | — | — | US | claimed |
| WO-2007141473-A1 | N-(BENZOYL)-O- [2- (PYRIDIN- 2 -YLAMINO) ETHYL] -L-TYROSINE DERIVATIVES AND RELATED COMPOUNDS AS A5B1 ANTAGONISTS FOR THE TREATMENT OF SOLID TUMORS | ASTRAZENECA AB (SE) | 2007-12-13 | — | — | WO | claimed |
| CN-112654621-B | Substituted naphthyridinone compounds useful as T cell activators | 百时美施贵宝公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-117836296-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-04-05 | — | — | CN | disclosed |
| US-20230303608-A1 | DITHIOLENE METAL COMPLEXES | BASF SCHWEIZ AG (CH) | 2023-09-28 | — | — | US | disclosed |
| EP-4182395-A1 | DITHIOLENE METAL COMPLEXES | BASF SE (DE) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022013081-A1 | DITHIOLENE METAL COMPLEXES | BASF SE (DE) | 2022-01-20 | — | — | WO | disclosed |
| US-5356935-A | Reductase inhibitors | ELI LILLY AND COMPANY (US) | 1994-10-18 | — | — | US | disclosed |
| US-5156669-A | Fungicides and plant growth regulators | BASF AKTIENGESELLSCHAFT (DE) | 1992-10-20 | — | — | US | disclosed |
| EP-0144853-B1 | SEMICARBAZIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |
| US-4725608-A | ANTIINFLAMMATORY, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-02-16 | — | — | US | disclosed |
| EP-0144853-A2 | Semicarbazide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |