SCHEMBL4579542

SCHEMBL4579542

O=C(NCCO)c1cc2ccccc2cc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 1.00
KDM4E B2RXH2 2/20 1.00
ALDH1A1 P00352 1/20 1.00
CASP1 P29466 1/20 1.00
CASP7 P55210 1/20 1.00
MEN1 O00255 3/20 0.65
KMT2A Q03164 3/20 0.65
GAA P10253 2/20 0.65
MITF O75030 1/20 0.65
NCOA1 Q15788 1/20 0.65
TDP1 Q9NUW8 1/20 0.65
NCOA3 Q9Y6Q9 1/20 0.65
PTGS1 P23219 1/20 0.58
PTGS2 P35354 1/20 0.58
SIRT1 Q96EB6 1/20 0.58
NPC1 O15118 6/20 0.57
MAPK1 P28482 1/20 0.57
CACNA1B Q00975 1/20 0.52
APBA1 Q02410 1/20 0.52
RAB9A P51151 4/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11439147 0.91 MAPT (0.84) MAPTKDM4EALDH1A1CASP1CASP7
SCHEMBL11333817 0.90 MAPT (0.82) MAPTKDM4EALDH1A1CASP1CASP7
SCHEMBL11568743 0.85 MAPT (0.74) MAPTKDM4EALDH1A1CASP1CASP7
SCHEMBL9312831 0.85 MAPT (0.74) MAPTKDM4EALDH1A1CASP1CASP7
SCHEMBL14263560 0.84 MAPT (0.73) MAPTKDM4EALDH1A1CASP1CASP7
SCHEMBL9828628 0.84 MAPT (0.72) MAPTKDM4EALDH1A1CASP1CASP7
Hydrochloric Acid SCHEMBL10348698 0.84 MAPT (0.72) MAPTKDM4EALDH1A1CASP1CASP7
SCHEMBL11133405 0.83 MAPT (0.70) MAPTKDM4EALDH1A1CASP1CASP7
SCHEMBL10348641 0.83 MAPT (0.70) MAPTKDM4EALDH1A1CASP1CASP7
SCHEMBL8928471 0.82 KDM4E (0.69) MAPTKDM4EALDH1A1CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5407777-A Diazo-type recording material comprising a 1-phenyl-3-pyrazolidone(phenidone) as an anti-oxidant FUJI PHOTO FILM CO., LTD. (JP) 1995-04-18 US claimed
US-5328796-A Diazo type recording material utilizing microencapsulated diazo compound, a coupler and a hydroxyphenylsulfone derivative FUJI PHOTO FILM CO., LTD. (JP) 1994-07-12 US claimed
US-4304831-A ELECTROGRAPHY; COPIES RICOH CO., LTD. (JP) 1981-12-08 US claimed
US-4157892-A COLORING AGENT IS CHEMICALLY COUPLED TO POLYMER TOYO CONTACT LENS COMPANY, LIMITED (JP) 1979-06-12 US claimed
JP-61017140-A None JP disclosed
US-8895637-B2 Environment-friendly antifoulants for the prevention of biofouling UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH (US) 2014-11-25 US disclosed
US-20140051751-A1 ENVIRONMENT-FRIENDLY ANTIFOULANTS FOR THE PREVENTION OF BIOFOULING THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2014-02-20 US disclosed
US-7399569-B2 Method for producing microcapsules, microcapsules, recording material, and heat-sensitive recording material FUJIFILM CORPORATION (JP) 2008-07-15 US disclosed
US-7270928-B2 Isocyanate composition, microcapsule and production method thereof, and recording material FUJIFILM CORPORATION (JP) 2007-09-18 US disclosed
EP-1382385-B1 Microcapsule and process for manufacturing the same FUJIFILM CORP (JP) 2007-03-21 EP disclosed
US-7011922-B2 Thermal recording material FUJI PHOTO FILM CO., LTD. (JP) 2006-03-14 US disclosed
US-20050260518-A1 Heat sensitive recording material and microcapsule FUJI PHOTO FILM CO., LTD. 2005-11-24 US disclosed
US-4304831-A ELECTROGRAPHY; COPIES RICOH CO., LTD. (JP) 1981-12-08 US disclosed
EP-0023673-A2 Device for performing a heat-sensitive recording, heat-sensitive recording sheet, and a method for performing a heat-sensitive recording KABUSHIKI KAISHA TOSHIBA (JP) 1981-02-11 EP disclosed
US-4225662-A 5-(ACETOACETAMIDO)BENZIMIDAZOLIN-2-ONE YELLOW COUPLERS RICOH COMPANY, LTD. (JP) 1980-09-30 US disclosed
US-4192683-A METAL SULFATE OF ALKYLPHENOL ETHYLENE OXIDE ADDUCT KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-03-11 US disclosed
US-4157892-A COLORING AGENT IS CHEMICALLY COUPLED TO POLYMER TOYO CONTACT LENS COMPANY, LIMITED (JP) 1979-06-12 US disclosed
US-4155762-A ALKALI OR ALKALINE EARTH METAL SALT OF AMINO CARBOXYLIC OR SULFONIC ACID RICOH CO., LTD. (JP) 1979-05-22 US disclosed
US-4148646-A FOR MAKING DUPLICATES OF X-RAY FILMS TRANS WORLD TECHNOLOGY LABORATORIES, INC. (US) 1979-04-10 US disclosed
US-4094681-A Image amplification of negative-working diazo materials TRANS WORLD TECHNOLOGY LABORATORIES, INC. (US) 1978-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140051751-A1 ENVIRONMENT-FRIENDLY ANTIFOULANTS FOR THE PREVENTION OF BIOFOULING TRPV1, CNR2, CNR1 MAPT 2864/4885KDM4E 1735/4885ALDH1A1 1736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.