SCHEMBL4579550

SCHEMBL4579550

CN1CCN(CC(O)COc2ccc(OCC(O)CN3CCN(C)CC3)cc2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 1.00
GLA P06280 1/20 1.00
USP2 O75604 1/20 0.77
TSHR P16473 1/20 0.77
ATM Q13315 1/20 0.71
L3MBTL1 Q9Y468 1/20 0.69
CYP2D6 P10635 1/20 0.69
CYP2C19 P33261 1/20 0.69
MAPT P10636 1/20 0.68
KMT2A Q03164 4/20 0.68
MEN1 O00255 3/20 0.68
HTT P42858 1/20 0.68
RAD52 P43351 1/20 0.68
POLB P06746 1/20 0.66
ALDH1A1 P00352 1/20 0.63
LMNA P02545 1/20 0.63
CACNA1G O43497 1/20 0.62
KCNH2 Q12809 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13246354 0.94 KDM4E (0.88) KDM4EGLAUSP2TSHRATM
SCHEMBL10772849 0.93 KDM4E (0.86) KDM4EGLAUSP2TSHRATM
SCHEMBL16314568 0.93 KDM4E (0.86) KDM4EGLAUSP2TSHRATM
SCHEMBL6131254 0.92 KDM4E (0.85) KDM4EGLAUSP2TSHRATM
SCHEMBL4578208 0.87 KDM4E (0.85) KDM4EGLAUSP2TSHRATM
SCHEMBL4579320 0.87 USP2 (1.00) KDM4EGLAUSP2TSHRATM
SCHEMBL16371128 0.86 KDM4E (0.77) KDM4EGLAUSP2TSHRL3MBTL1
SCHEMBL6246091 0.83 KDM4E (0.70) KDM4EGLAUSP2TSHRATM
SCHEMBL19173791 0.83 MEN1 (0.98) KDM4EGLAUSP2TSHRATM
SCHEMBL19173708 0.83 MEN1 (0.98) KDM4EGLAUSP2TSHRATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1298490-B1 Photopolymerizable composition and recording material FUJIFILM CORP (JP) 2008-08-13 EP disclosed
US-7399569-B2 Method for producing microcapsules, microcapsules, recording material, and heat-sensitive recording material FUJIFILM CORPORATION (JP) 2008-07-15 US disclosed
US-7300738-B2 Azolinyl acetic acid derivative and azolinyl acetic acid derivative containing recording material FUJIFILM CORPORATION (JP) 2007-11-27 US disclosed
US-7205083-B2 Recording material FUJIFILM CORPORATION (JP) 2007-04-17 US disclosed
EP-1254780-B1 Recording material FUJI PHOTO FILM CO LTD (JP) 2007-01-03 EP disclosed
US-7157407-B2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 2007-01-02 US disclosed
US-7094731-B2 Recording material FUJI PHOTO FILM CO., LTD. (JP) 2006-08-22 US disclosed
EP-1253466-B1 Diazonium salt and heat-sensitive recording material FUJI PHOTO FILM CO LTD (JP) 2006-05-31 EP disclosed
US-20050272604-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2005-12-08 US disclosed
EP-1275519-B1 Recording material FUJI PHOTO FILM CO LTD (JP) 2005-08-31 EP disclosed
US-5935757-A HIGH COLOR DEVELOPING SENSITIVITY AND EXCELLENT STORABILITY. USING AN ESTER- OR AMIDE CONTAINING SULFOAMIDOBENZENE IN A LAYER CONTAINING A DIAZONIUM SALT AND A REACTIVE COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1999-08-10 US disclosed
EP-0930529-A1 Heat-sensitive recording material Fuji Photo Film., Ltd. (JP) 1999-07-21 EP disclosed
US-5925489-A CONTAINING DIAZONIUM SALT AND PYRROLOPYRIMIDINE COUPLER WHICH REACT WHEN HEATED TO DEVELOP VIOLET TO CYAN COLORS, IMAGE QUALITY AND STABILITY, SHELF LIFE FUJI PHOTO FILM CO., LTD. (JP) 1999-07-20 US disclosed
US-5866293-A CONTAINING DIAZO COMPOUND AND PYRAZOLONE COUPLER; STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1999-02-02 US disclosed
EP-0827020-A1 Thermal recording material FUJI PHOTO FILM CO., LTD. (JP) 1998-03-04 EP disclosed
EP-0809145-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1997-11-26 EP disclosed
US-5683850-A HAVING EXCELLENT RAW STOCK STORABILITY AND IMAGE STORAGE CHARACTERISTICS FUJI PHOTO FILM CO., LTD. (JP) 1997-11-04 US disclosed
US-5543260-A RED COLOR; STORAGE STABILITY; COLORFASTNESS FUJI PHOTO FILM CO., LTD. (JP) 1996-08-06 US disclosed
US-5236800-A Support; diazo compound; no solvnet; coupling component; basic substance; shelf life FUJI PHOTO FILM CO., LTD. (JP) 1993-08-17 US disclosed
US-4975353-A Support and layer of diazo compound, coupling component for coloration and basic compound FUJI PHOTO FILM CO., LTD. (JP) 1990-12-04 US disclosed