SCHEMBL6131254

SCHEMBL6131254

CN1CCN(CC(O)COc2ccccc2)CC1

nearest known ligand 0.85

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.85
GLA P06280 1/20 0.85
L3MBTL1 Q9Y468 2/20 0.82
TSHR P16473 2/20 0.73
CYP2D6 P10635 1/20 0.73
HIF1A Q16665 1/20 0.73
MEN1 O00255 3/20 0.70
KMT2A Q03164 3/20 0.70
ALDH1A1 P00352 2/20 0.67
LMNA P02545 1/20 0.67
USP2 O75604 1/20 0.66
DRD4 P21917 4/20 0.64
DRD2 P14416 3/20 0.64
DRD3 P35462 3/20 0.64
MAPT P10636 1/20 0.64
MAPK1 P28482 1/20 0.62
HTT P42858 2/20 0.61
ATM Q13315 1/20 0.60
RAD52 P43351 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4579550 0.92 KDM4E (1.00) KDM4EGLAL3MBTL1TSHRCYP2D6
SCHEMBL4577971 0.92 L3MBTL1 (0.97) KDM4EGLAL3MBTL1TSHRCYP2D6
SCHEMBL3970369 0.92 L3MBTL1 (0.97) KDM4EGLAL3MBTL1TSHRCYP2D6
SCHEMBL11240406 0.92 L3MBTL1 (0.97) KDM4EGLAL3MBTL1TSHRCYP2D6
SCHEMBL22014323 0.88 L3MBTL1 (0.82) KDM4EGLAL3MBTL1TSHRCYP2D6
SCHEMBL13246354 0.87 KDM4E (0.88) KDM4EGLAL3MBTL1TSHRCYP2D6
SCHEMBL25010831 0.86 KDM4E (1.00) KDM4EL3MBTL1TSHRCYP2D6HIF1A
SCHEMBL11537591 0.86 KDM4E (1.00) KDM4EL3MBTL1TSHRCYP2D6HIF1A
SCHEMBL25010832 0.86 KDM4E (1.00) KDM4EL3MBTL1TSHRCYP2D6HIF1A
SCHEMBL16314568 0.85 KDM4E (0.86) KDM4EGLAL3MBTL1TSHRCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1598208-A2 Heat-sensitive recording material Fuji Photo Film Co., Ltd. (JP) 2005-11-23 EP disclosed
EP-1598206-A2 Heat sensitive recording material and microcapsule FUJI PHOTO FILM CO., LTD. (JP) 2005-11-23 EP disclosed
US-20050187102-A1 Method for producing microcapsules, microcapsules, recording material, and heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2005-08-25 US disclosed
US-6824953-B2 POLYMERIZABLE COMPOUND HAVING AN ETHYLENIC UNSATURATED BOND, A METHINE DYE, AND A RADICAL GENERATOR THAT INTERACTS WITH THE DYE TO GENERATE A RADICAL FUJI PHOTO FILM CO., LTD. (JP) 2004-11-30 US disclosed
US-20030158038-A1 Guanidine compound and heat sensitive recording material FUJI PHOTO FILM CO., LTD. 2003-08-21 US disclosed
US-20020182530-A1 Polymerizable compound having an ethylenic unsaturated bond, a methine dye, and a radical generator that interacts with the dye to generate a radical FUJI PHOTO FILM CO., LTD. 2002-12-05 US disclosed
US-6416922-B2 DRY PROCESSING PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 2002-07-09 US disclosed
US-20010019806-A1 Azomethine dye precursor, image-forming material, and image-forming method FUJIFILM CORPORATION (JP) 2001-09-06 US disclosed
US-5998082-A DIHYDROCARBYLOXYPHENYL DIAZONIUM COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1999-12-07 US disclosed
EP-0327318-B1 Heat-sensitive recording materials FUJI PHOTO FILM CO LTD (JP) 1995-07-19 EP disclosed
EP-0337734-B1 Heat-developable diazo copying material FUJI PHOTO FILM CO LTD (JP) 1995-03-08 EP disclosed
EP-0327318-A2 Heat-sensitive recording materials FUJI PHOTO FILM CO., LTD. (JP) 1989-08-09 EP disclosed
US-4170653-A Antidepressant naphthyloxy piperidino and pyrrolidino propanol ethers Ayerst McKenna and Harrison Limited (CA) 1979-10-09 US disclosed
US-4060613-A ANTIDEPRESSANT AYERST MCKENNA AND HARRISON LTD. (CA) 1977-11-29 US disclosed