Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29788008 | 1.00 | HDAC4 (0.53) | HDAC4HDAC2HDAC8PTGS2SMN1; SMN2 | |
| SCHEMBL10536041 | 0.90 | HDAC4 (0.57) | HDAC4HDAC2HDAC8PTGS2SMN1; SMN2 | |
| Adamantane SCHEMBL28906651 | 0.89 | PTGS2 (0.47) | HDAC4HDAC2HDAC8PTGS2SMN1; SMN2 | |
| SCHEMBL28039230 | 0.89 | PDE4B (0.50) | SMN1; SMN2ALDH1A1POLBKDM4EMAPT | |
| SCHEMBL4359012 | 0.84 | IDO1 (0.55) | SMN1; SMN2ERN1ALDH1A1IDO1TDO2 | |
| SCHEMBL29446789 | 0.84 | IDO1 (0.55) | SMN1; SMN2ERN1ALDH1A1IDO1TDO2 | |
| SCHEMBL3643547 | 0.84 | NPC1 (0.54) | HDAC4HDAC2HDAC8PTGS2SMN1; SMN2 | |
| SCHEMBL21609119 | 0.84 | NPC1 (0.42) | PTGS2SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL13744810 | 0.84 | TP53 (0.51) | SMN1; SMN2NPC1RAB9AALDH1A1POLB | |
| SCHEMBL28081752 | 0.84 | ALOX5AP (0.48) | HDAC4HDAC2HDAC8PTGS2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101654401-B | Asymmetrical biphenyl compounds, medicinal compositions containing same and application of medicinal compositions | INST PHARM & TOXICOLOGY AMMS | 2013-06-05 | — | — | CN | claimed |
| CN-101898959-A | Biphenyl compound and preparation method and use thereof | UNIV JINAN | 2010-12-01 | — | — | CN | claimed |
| CN-101654401-A | Asymmetrical biphenyl compounds, medicinal compositions containing same and application of medicinal compositions | POISON MED INST PLA MED ACAD | 2010-02-24 | — | — | CN | claimed |
| JP-1011187-A | — | — | None | — | — | JP | disclosed |
| CN-113874352-A | Arylamine compound and use thereof | 日产化学株式会社 | 2021-12-31 | — | — | CN | disclosed |
| CN-108727397-A | phenanthridine derivatives | 潍坊医学院 | 2018-11-02 | — | — | CN | disclosed |
| CN-108467370-A | Triazole naphthoquinones biaryl（It is miscellaneous）Ring derivatives | 四川大学 | 2018-08-31 | — | — | CN | disclosed |
| CN-105209514-B | Method for producing epoxy resin containing biphenyl skeleton | DIC株式会社 | 2017-04-12 | — | — | CN | disclosed |
| CN-105209514-A | Method for producing epoxy resin containing biphenyl skeleton | DAINIPPON INK & CHEMICALS | 2015-12-30 | — | — | CN | disclosed |
| CN-102875599-B | Three tooth Phosphine ligands and the application in linear hydroformylation and similar reaction thereof | WUHAN UNIVERSITY (CN) | 2015-11-04 | — | — | CN | disclosed |
| CN-105012595-A | Traditional Chinese medicine composition for treating upper respiratory tract infection, and preparation method thereof | LI DONGHUA | 2015-11-04 | — | — | CN | disclosed |
| CN-102875599-A | Novel tridentate phosphine ligand and application of same to linear hydroformylation and similar reactions | UNIV WUHAN | 2013-01-16 | — | — | CN | disclosed |
| CN-101898959-A | Biphenyl compound and preparation method and use thereof | UNIV JINAN | 2010-12-01 | — | — | CN | disclosed |
| CN-101654401-A | Asymmetrical biphenyl compounds, medicinal compositions containing same and application of medicinal compositions | POISON MED INST PLA MED ACAD | 2010-02-24 | — | — | CN | disclosed |
| US-20080132503-A1 | Inhibitors of Histone Deacetylase | METHYLGENE INC. (CA) | 2008-06-05 | — | — | US | disclosed |
| CN-1177909-C | Substituted poly (arylenevinylenes), method for the production thereof and use thereof in electroluminescent elements | — | 2004-12-01 | — | — | CN | disclosed |
| CN-1147298-C | Prevention and curing agent for c attenuation living vaccine | 卫材株式会社 | 2004-04-28 | — | — | CN | disclosed |
| CN-1280607-A | Substituted poly (arylene vinglenes), method for producing the same, and their use in electroluminescent elements | AKSIWA CO LTD (DE) | 2001-01-17 | — | — | CN | disclosed |
| CN-1137895-A | Prevention and curing agent for c attenuation living vaccine | EISAI CO LTD (JP) | 1996-12-18 | — | — | CN | disclosed |
| JP-S6411187-A | ANTIOXIDANT | NIPPON KAYAKU KK | 1989-01-13 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132503-A1 | Inhibitors of Histone Deacetylase | HDAC1, HDAC5, HDAC3 | HDAC4 8/4885HDAC2 5/4885HDAC8 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.