SCHEMBL4579976

SCHEMBL4579976

C=C(CC(=O)CC(=O)O)C(=O)O

nearest known ligand 0.74

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.58
HSD17B10 Q99714 1/20 0.58
LDHA P00338 1/20 0.42
SRR Q9GZT4 1/20 0.42
TET2 Q6N021 5/20 0.37
TET3 O43151 1/20 0.37
TET1 Q8NFU7 1/20 0.37
GRIK1 P39086 1/20 0.36
GRIK2 Q13002 1/20 0.36
GRM1 Q13255 1/20 0.36
GRM2 Q14416 1/20 0.36
KDM4E B2RXH2 1/20 0.33
TSHR P16473 1/20 0.33
MMP12 P39900 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Itaconate SCHEMBL286967 0.85 ALOX15 (0.75) ALOX15HSD17B10LDHASRRTET2
Itaconate SCHEMBL21523 0.85
Itaconate SCHEMBL29886131 0.85
Itaconate SCHEMBL28352485 0.83 ALOX15 (0.65) ALOX15HSD17B10LDHASRRTET2
Itaconate SCHEMBL2397428 0.82 ALOX15 (0.71) ALOX15HSD17B10LDHASRRTET2
Itaconate SCHEMBL9244093 0.82 ALOX15 (0.71) ALOX15HSD17B10LDHASRRTET2
Itaconate SCHEMBL1888723 0.82 ALOX15 (0.71) ALOX15HSD17B10LDHASRRTET2
Itaconate SCHEMBL10757202 0.82 ALOX15 (0.71) ALOX15HSD17B10LDHASRRTET2
Itaconate SCHEMBL8074438 0.82 ALOX15 (0.71) ALOX15HSD17B10LDHASRRTET2
Itaconate SCHEMBL18554417 0.82 ALOX15 (0.71) ALOX15HSD17B10LDHASRRTET2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4217396-A CROSSLINKED, COLORLESS ARMSTRONG CORK COMPANY (US) 1980-08-12 US claimed
CN-114729253-A Michael addition hardening synthetic resin for chemical fixing technology 费希尔厂有限责任两合公司 2022-07-08 CN disclosed
WO-2021110622-A1 MICHAEL REACTION-CURING SYNTHETIC RESIN FOR USE IN CHEMICAL FASTENING TECHNOLOGY FISCHERWERKE GMBH & CO. KG (DE) 2021-06-10 WO disclosed
CN-106660306-B Incombustible sheet and method for producing same 凸版印刷株式会社 2020-01-21 CN disclosed
EP-1954748-B1 PREPREGS AND CURED IN PLACE SOLID SURFACES PREPARED THEREFROM ASHLAND LICENSING & IP LLC (US) 2018-09-26 EP disclosed
US-8741978-B2 Prepregs and cured in place solid surfaces prepared therefrom ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC (US) 2014-06-03 US disclosed
EP-1756035-B1 RADIATION-CURABLE COATINGS FOR METAL SUBSTRATES FROM MULTIFUNCTIONAL ACRYLATE OLIGOMERS ASHLAND LICENSING & INTELLECTU (US) 2013-08-14 EP disclosed
EP-1954748-A2 PREPREGS AND CURED IN PLACE SOLID SURFACES PREPARED THEREFROM Ashland Licensing and Intellectual Property LLC (US) 2008-08-13 EP disclosed
US-7407707-B2 Radiation-curable coatings for metal substrates from multifunctional acrylate oligomers ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC (US) 2008-08-05 US disclosed
US-20070225443-A1 Prepregs and cured in place solid surfaces prepared therefrom ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC (US) 2007-09-27 US disclosed
US-20050272830-A1 Radiation-curable coatings for metal substrates from multifunctional acrylate oligomers ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC (US) 2005-12-08 US disclosed
WO-2005108344-A1 RADIATION-CURABLE COATINGS FOR METAL SUBSTRATES FROM MULTIFUNCTIONAL ACRYLATE OLIGOMERS ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC (US) 2005-11-17 WO disclosed
US-6706414-B1 Liquid uncrosslinked Michael addition oligomers prepared in the presence of a catalyst having both an epoxy moiety and a quaternary salt ASHLAND INC. 2004-03-16 US disclosed
US-5945489-A Liquid oligomers containing unsaturation ASHLAND, INC. (US) 1999-08-31 US disclosed
EP-0664999-B1 Use of heat curable compositions as dental material IVOCLAR AG (LI) 1999-03-24 EP disclosed
US-5539017-A BETA-DICARBONYL COMPOUNDS AND ALPHA,BETA-UNSATURATED ESTERS OF CARBOXYLIC ACIDS IVOCLAR AG (LI) 1996-07-23 US disclosed
EP-0664999-A1 Use of heat curable compositions as dental material IVOCLAR AG (LI) 1995-08-02 EP disclosed
US-4217396-A CROSSLINKED, COLORLESS ARMSTRONG CORK COMPANY (US) 1980-08-12 US disclosed
US-4217396-A CROSSLINKED, COLORLESS ARMSTRONG CORK COMPANY (US) 1980-08-12 US disclosed
US-4217396-A CROSSLINKED, COLORLESS ARMSTRONG CORK COMPANY (US) 1980-08-12 US disclosed