Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 12/20 | 0.76 |
| ▸ | PKLR | P30613 | 10/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2239830 | 0.87 | PKM (1.00) | PKMPKLRPOLBNPC1RAB9A | |
| SCHEMBL4555879 | 0.81 | PKM (0.81) | PKMPKLRTSHRSMN1; SMN2 | |
| SCHEMBL29518915 | 0.81 | PKM (0.81) | PKMPKLRTSHRSMN1; SMN2 | |
| SCHEMBL7305504 | 0.81 | PKM (0.49) | PKMPKLRTSHRSMN1; SMN2POLB | |
| SCHEMBL3343329 | 0.81 | PKM (0.58) | PKMPKLRTSHRSMN1; SMN2POLB | |
| SCHEMBL17808926 | 0.79 | PKM (0.76) | PKMPKLRTSHRTP53MAPT | |
| SCHEMBL19871301 | 0.77 | PKM (0.79) | PKMPKLRPOLB | |
| SCHEMBL17800942 | 0.75 | PKM (0.74) | PKMPKLRPOLBNPC1RAB9A | |
| SCHEMBL29483599 | 0.75 | PKM (0.66) | PKMPKLRTSHRSMN1; SMN2POLB | |
| SCHEMBL1722746 | 0.74 | PKM (1.00) | PKMPKLRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312349-A1 | METHOD OF MAKING AND USING MEMBRANE | GENERAL ELECTRIC COMPANY (US) | 2008-12-18 | — | — | US | disclosed |
| US-20080203012-A1 | MEMBRANE, APPARATUS, AND ASSOCIATED METHOD | GENERAL ELECTRIC COMPANY (US) | 2008-08-28 | — | — | US | disclosed |
| US-20080207822-A1 | COMPOSITION AND ASSOCIATED METHOD | GENERAL ELECTRIC COMPANY (US) | 2008-08-28 | — | — | US | disclosed |
| WO-2008103599-A2 | COMPOSITION, ITS USE IN THE PREPARATION OF MEMBRANES, AND SYSTEMS COMPRISING THE MEMBRANES | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-08-28 | — | — | WO | disclosed |