SCHEMBL4580463

SCHEMBL4580463

NNS(=O)(=O)c1ccccc1Oc1ccccc1S(=O)(=O)O

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 9/20 0.41
TTR P02766 1/20 0.36
MRGPRX1 Q96LB2 1/20 0.36
HSD17B10 Q99714 1/20 0.35
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34
CA12 O43570 1/20 0.34
CA6 P23280 1/20 0.34
CA5A P35218 1/20 0.34
CA7 P43166 1/20 0.34
CA5B Q9Y2D0 1/20 0.34
MYC P01106 1/20 0.34
KAT6A Q92794 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL128257 0.91 CASP1 (0.42) CASP1MRGPRX1CA1CA2CA9
SCHEMBL30695942 0.91 CASP1 (0.42) CASP1MRGPRX1CA1CA2CA9
Hydrazine SCHEMBL29100189 0.85 TTR (0.42) CASP1TTRHSD17B10CA1CA2
SCHEMBL5698446 0.85 MYC (0.42) CASP1TTRHSD17B10CA2CA9
SCHEMBL6160456 0.83 SMN1; SMN2 (0.46) CASP1TTRHSD17B10CA2CA9
SCHEMBL28521154 0.83 MYC (0.41) CASP1TTRHSD17B10CA2CA9
SCHEMBL4962913 0.83 MYC (0.41) CASP1TTRHSD17B10CA2CA9
Phosphoric Acid SCHEMBL9300595 0.81 CASP1 (0.37) CASP1MRGPRX1CA1CA2CA9
SCHEMBL30143351 0.80 MYC (0.43) CASP1TTRHSD17B10CA1CA2
SCHEMBL11400434 0.77 SMN1; SMN2 (0.49) CASP1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7462146-B2 Roller member, and process for its manufacture CANON KABUSHIKI KAISHA (JP) 2008-12-09 US disclosed
CN-100346237-C Roller member, and process for its manufacture CANON KK (JP) 2007-10-31 CN disclosed
CN-1591217-A Roller member, and process for its manufacture CANON KK (JP) 2005-03-09 CN disclosed
US-20050049127-A1 Roller member, and process for its manufacture CANON KABUSHIKI KAISHA (JP) 2005-03-03 US disclosed