SCHEMBL458051

SCHEMBL458051

c1ccc(-n2c3cc(-c4cccc5c4sc4ccccc45)ccc3c3ccc(-c4cccc5c4sc4ccccc45)cc32)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.57
PRKDC P78527 8/20 0.45
ATM Q13315 2/20 0.41
KDM4E B2RXH2 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PARP14 Q460N5 1/20 0.39
PIK3CD O00329 2/20 0.36
PIK3CB P42338 2/20 0.36
BRD4 O60885 1/20 0.36
PIK3CA P42336 1/20 0.36
MTOR P42345 1/20 0.36
PIK3CG P48736 1/20 0.36
KCNH2 Q12809 1/20 0.36
BRDT Q58F21 1/20 0.36
TNKS O95271 1/20 0.35
TNKS2 Q9H2K2 1/20 0.35
F9 P00740 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MAPT P10636 4/20 0.34
RXFP1 Q9HBX9 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10165715 0.97 ALOX5 (0.54) ALOX5PRKDCATMKDM4EL3MBTL1
SCHEMBL10165763 0.96 ALOX5 (0.53) ALOX5PRKDCATMKDM4EL3MBTL1
SCHEMBL21365465 0.95 ALOX5 (0.54) ALOX5PRKDCATMKDM4EL3MBTL1
SCHEMBL10165758 0.94 ALOX5 (0.51) ALOX5PRKDCATMKDM4EL3MBTL1
SCHEMBL26060131 0.93 ALOX5 (0.50) ALOX5PRKDCATMKDM4EL3MBTL1
SCHEMBL10165756 0.92 ALOX5 (0.49) ALOX5PRKDCATMKDM4EL3MBTL1
SCHEMBL10165724 0.92 ALOX5 (0.52) ALOX5PRKDCATMKDM4EL3MBTL1
SCHEMBL18505096 0.92 ALOX5 (0.49) ALOX5PRKDCATMKDM4EL3MBTL1
SCHEMBL10165728 0.92 ALOX5 (0.49) ALOX5PRKDCATMKDM4EL3MBTL1
SCHEMBL18505092 0.92 ALOX5 (0.49) ALOX5PRKDCATMKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10833282-B2 Light-emitting element and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-11-10 US disclosed
US-10833282-B2 Light-emitting element and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-11-10 US disclosed
US-20170288153-A1 Light-Emitting Element and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-10-05 US disclosed
US-20170288153-A1 Light-Emitting Element and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-10-05 US disclosed
US-20170288153-A1 Light-Emitting Element and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-10-05 US disclosed
US-9735372-B2 Light-emitting element and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-08-15 US disclosed
US-9735372-B2 Light-emitting element and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-08-15 US disclosed
US-9735372-B2 Light-emitting element and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-08-15 US disclosed
US-20150287934-A1 Light-Emitting Element and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-10-08 US disclosed
US-20150287934-A1 Light-Emitting Element and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-10-08 US disclosed
US-8673459-B2 Light-emitting element and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-03-18 US disclosed
US-8673459-B2 Light-emitting element and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-03-18 US disclosed
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-19 US disclosed
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-19 US disclosed
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-19 US disclosed
US-20120074390-A1 Light-Emitting Element and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-29 US disclosed
US-20120074390-A1 Light-Emitting Element and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-29 US disclosed
US-20120074390-A1 Light-Emitting Element and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-29 US disclosed
WO-2012033108-A1 LIGHT-EMITTING ELEMENT AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-15 WO disclosed
WO-2012033108-A1 LIGHT-EMITTING ELEMENT AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10833282-B2 Light-emitting element and electronic device SLC39A3, SLC19A2, SLC39A14 ALOX5 1257/4885PRKDC 2685/4885ATM 3681/4885
US-20150287934-A1 Light-Emitting Element and Electronic Device SLC39A3, SLC19A2, SLC39A14 ALOX5 1257/4885PRKDC 2685/4885ATM 3681/4885
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element NUTF2, BRI3BP, CLINT1 ALOX5 1931/4885PRKDC 2968/4885ATM 2465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.