SCHEMBL4580549

SCHEMBL4580549

c1ccc(-c2cccc3ccccc23)c(Nc2ccc(-c3ccc(-c4cccc5c4[nH]c4ccccc45)cc3)cc2)c1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PARP14 Q460N5 15/20 0.48
BCHE P06276 1/20 0.47
KIF11 P52732 1/20 0.44
ALDH1A1 P00352 1/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
CDC25B P30305 1/20 0.42
ATM Q13315 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CDK4 P11802 2/20 0.41
CCND1 P24385 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28795757 0.88 PARP14 (0.49) PARP14CDK4CCND1
SCHEMBL29787771 0.88 PARP14 (0.49) PARP14CDK4CCND1
SCHEMBL22189182 0.85 BCHE (0.55) PARP14BCHEKIF11TP53
SCHEMBL28697631 0.85 PARP14 (0.48) PARP14BCHEKIF11CDK4CCND1
SCHEMBL21905509 0.85 CDC25B (0.53) ALDH1A1TP53CYP3A4HPGDALOX15
SCHEMBL30035585 0.85 CDC25B (0.53) ALDH1A1TP53CYP3A4HPGDALOX15
SCHEMBL347485 0.85 ALDH1A1 (0.56) ALDH1A1TP53CYP3A4HPGDALOX15
SCHEMBL24910923 0.83 CDC25B (0.55) ALDH1A1TP53CYP3A4HPGDALOX15
SCHEMBL29830213 0.83 CDC25B (0.55) ALDH1A1TP53CYP3A4HPGDALOX15
SCHEMBL28066221 0.83 BCHE (0.59) PARP14BCHEKIF11ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7396599-B2 Binuclear organometallic complexes and organic electroluminescent display device using the same SAMSUNG SDI CO., LTD. (KR) 2008-07-08 US disclosed