Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL11457787 | 0.82 | ALDH1A1 (0.36) | KDM4EMEN1USP2ALDH1A1MAPT | |
| Acetic Acid SCHEMBL29068732 | 0.82 | FFAR3 (0.50) | FFAR3LCKFYNKDM4EALDH1A1 | |
| Acetic Acid SCHEMBL30450394 | 0.82 | FFAR3 (0.50) | FFAR3LCKFYNKDM4EALDH1A1 | |
| Diethanolamine SCHEMBL3630770 | 0.80 | FFAR3 (0.41) | FFAR3LCKFYNKDM4EMEN1 | |
| SCHEMBL590441 | 0.78 | — | — | |
| Diethanolamine SCHEMBL9790976 | 0.77 | FFAR3 (0.44) | FFAR3LCKFYNKDM4EMEN1 | |
| Diethanolamine SCHEMBL502768 | 0.77 | FFAR3 (0.44) | FFAR3LCKFYNKDM4EMEN1 | |
| Water SCHEMBL11082396 | 0.75 | — | — | |
| SCHEMBL2528322 | 0.75 | — | — | |
| Acetic Acid SCHEMBL28708640 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906415-B2 | Device having zinc oxide semiconductor and indium/zinc electrode | XEROX CORPORATION (US) | 2011-03-15 | — | — | US | disclosed |
| US-20080023698-A1 | Device having zinc oxide semiconductor and indium/zinc electrode | XEROX CORPORATION | 2008-01-31 | — | — | US | disclosed |
| US-20070287221-A1 | Fabrication process for crystalline zinc oxide semiconductor layer | XEROX CORPORATION | 2007-12-13 | — | — | US | disclosed |