⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3060893 | 0.79 | — | — | |
| SCHEMBL75926 | 0.79 | — | — | |
| SCHEMBL456256 | 0.79 | DAO (0.32) | — | |
| SCHEMBL1680680 | 0.76 | — | — | |
| SCHEMBL7909701 | 0.76 | — | — | |
| SCHEMBL25423722 | 0.75 | — | — | |
| SCHEMBL4700498 | 0.75 | — | — | |
| SCHEMBL13754484 | 0.75 | DAO (0.30) | — | |
| SCHEMBL23079299 | 0.75 | — | — | |
| SCHEMBL447798 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699572-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | Origenis GmbH (DE) | 2014-02-26 | — | — | EP | disclosed |
| WO-2012143143-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | ORIGENIS GMBH (DE) | 2012-10-26 | — | — | WO | disclosed |
| US-8008487-B2 | Substituted thieno[2,3-D]pyrimidines as fungicides | DOW AGROSCIENCES LLC (US) | 2011-08-30 | — | — | US | disclosed |
| US-8008487-B2 | Substituted thieno[2,3-D]pyrimidines as fungicides | DOW AGROSCIENCES LLC (US) | 2011-08-30 | — | — | US | disclosed |
| CN-100506801-C | Inhibitors of glycogen synthase kinase 3 | CHIRON CORP (US) | 2009-07-01 | — | — | CN | disclosed |
| EP-1328515-B1 | INDOLINE DERIVATIVES AND THEIR USE AS 5-HT2 RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2008-08-06 | — | — | EP | disclosed |
| EP-1343775-B1 | PIPERAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-06-04 | — | — | EP | disclosed |
| US-20080125455-A1 | Condensed indoline derivatives and their use as 5HT, in particular 5HT2C, Receptor ligands | VERNALIS RESEARCH LIMITED | 2008-05-29 | — | — | US | disclosed |
| US-20080114018-A1 | Condensed indoline derivatives and their use as 5HT, in particular 5HT2C, receptor ligands | VERNALIS RESEARCH LIMITED | 2008-05-15 | — | — | US | disclosed |
| US-20080090858-A1 | Condensed indoline derivatives and their use as 5HT, in particular 5HT2C, receptor ligands | VERNALIS RESEARCH LIMITED | 2008-04-17 | — | — | US | disclosed |
| WO-2000012482-A2 | INDAZOLE DERIVATIVES WITH 5-HT2 RECEPTOR ACTIVITY | VERNALIS RESEARCH LIMITED (GB) | 2000-03-09 | — | — | WO | disclosed |
| WO-2000012481-A2 | INDAZOLE DERIVATIVES WITH 5-HT2 RECEPTOR ACTIVITY________________ | VERNALIS RESEARCH LIMITED (GB) | 2000-03-09 | — | — | WO | disclosed |
| WO-2000012510-A1 | PYRROLOINDOLES, PYRIDOINDOLES AND AZEPINOINDOLES AS 5-HT2C AGONISTS | VERNALIS RESEARCH LIMITED (GB) | 2000-03-09 | — | — | WO | disclosed |
| WO-2000012475-A1 | INDOLINE DERIVATIVES AS 5-HT2B AND/OR 5-HT2C RECEPTOR LIGANDS | VERNALIS RESEARCH LIMITED (GB) | 2000-03-09 | — | — | WO | disclosed |
| WO-2000012502-A1 | PYRROLOQUINOLINES FOR TREATMENT OF OBESITY | VERNALIS RESEARCH LIMITED (GB) | 2000-03-09 | — | — | WO | disclosed |
| EP-0902788-A1 | NUCLEOSIDE DERIVATIVES, AND THEIR USE IN OLIGONUCLEOTIDE SYNTHESIS | CIS BIO INTERNATIONAL (FR) | 1999-03-24 | — | — | EP | disclosed |
| WO-1997042207-A1 | NUCLEOSIDE DERIVATIVES, AND THEIR USE IN OLIGONUCLEOTIDE SYNTHESIS | CIS BIO INTERNATIONAL (FR) | 1997-11-13 | — | — | WO | disclosed |
| EP-0691978-B1 | ELECTRONICALLY CONDUCTIVE POLYMER/NUCLEOTIDE COPOLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF | CIS BIO INT (FR) | 1997-10-08 | — | — | EP | disclosed |
| CN-1105989-A | Tricyclic 1-aminoethylpyrrol derivative | HOFFMANN LA ROCHE (CH) | 1995-08-02 | — | — | CN | disclosed |
| CN-1105989-A | Tricyclic 1-aminoethylpyrrol derivative | HOFFMANN LA ROCHE (CH) | 1995-08-02 | — | — | CN | disclosed |